Evidence map›Paper›PMID 42185458›Full record

ReviewAdvances in biochemical engineering/biotechnology2026

Challenging Pretreatment Technologies of Lignocellulosic Biomass.

Xinchuan Yuan, Guannan Shen, Qianqian Yang, Yin Cheng, Yiwei Chang, Yao Chen, Xingye Hu, Rui Zhai, Mingjie Jin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in biochemical engineering/biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xinchuan YuanSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, People's Republic of China.
Guannan ShenSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, People's Republic of China.
Qianqian YangSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, People's Republic of China.
Yin ChengSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, People's Republic of China.
Yiwei ChangSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, People's Republic of China.
Yao ChenSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, People's Republic of China.
Xingye HuSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, People's Republic of China.
Rui ZhaiSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, People's Republic of China.
Mingjie JinSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, People's Republic of China. jinmingjie@njust.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lignocellulosic biomass, derived from agricultural and forestry waste, is a promising renewable resource for biofuels and biochemicals. However, its recalcitrant structure, which is comprised of intertwined cellulose, hemicellulose, and lignin, hinders efficient conversion, necessitating pretreatment as a crucial step to disrupt this matrix and enhance enzymatic hydrolysis. Pretreatment methods are categorized based on their target components: hemicellulose depolymerization strategies such as acid pretreatment (e.g., inorganic, organic, and solid acids) and physicochemical methods like steam explosion improve sugar release but face challenges like inhibitor formation and high energy costs; lignin removal strategies, including alkaline, oxidative, and biological pretreatments, effectively degrade lignin yet struggle with reagent recovery and low working efficiency; and selective fractionation strategies, such as organosolv, ionic liquids, and deep eutectic solvents, aim for high-value utilization but encounter issues with solvent sustainability and costs. Emerging technologies like dry acid pretreatment with biodetoxification (DryPB), ammonia-based methods, and densifying lignocellulosic biomass with chemicals (DLC) offer improved efficiency, reduced waste, and high product yields, highlighting the need for future optimization in cost-effectiveness, selectivity, and integration for scalable biorefineries.

Indexed as

BiofuelsBiomassBiotechnologyLigninHydrolysisBiofuelsLigninlignocelluloseBiorefineryComponent targetingLignocellulosic biomassPretreatment strategySustainable conversion

Identifiers

PMID42185458

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.