Evidence map›Paper›PMID 42185490›Full record

ArticleNPJ digital medicine2026

CODE-II: a large-scale dataset for artificial intelligence in ECG analysis.

Petrus E O G B Abreu, Gabriela M M Paixão, Jiawei Li, Paulo R Gomes, Peter W Macfarlane, Ana C S Oliveira, Vinícius T Carvalho, Thomas B Schön, Antonio Luiz P Ribeiro, Antônio H Ribeiro

Abstract read
In one paragraph

Article in NPJ digital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Petrus E O G B AbreuFaculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil. petrusabreu@ufmg.br.
Gabriela M M PaixãoFaculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Jiawei LiUppsala University, Uppsala, Sweden.
Paulo R GomesTelehealth Center, Hospital das Clínicas, UFMG, Belo Horizonte, Brazil.
Peter W MacfarlaneUniversity of Glasgow, Glasgow, UK.
Ana C S OliveiraFaculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Vinícius T CarvalhoFaculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Thomas B SchönUppsala University, Uppsala, Sweden.
Antonio Luiz P RibeiroFaculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil. antonio.ribeiro@ebserh.gov.br.
Antônio H RibeiroUppsala University, Uppsala, Sweden. antonio.horta.ribeiro@it.uu.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data-driven methods for electrocardiogram (ECG) interpretation are rapidly progressing. Large datasets have enabled advances in artificial intelligence (AI) based ECG analysis, yet limitations in annotation quality, size, and scope remain major challenges. Here we present CODE-II, a large-scale real-world dataset of 2,735,269 12-lead ECGs from 2,093,807 adult patients collected by the Telehealth Network of Minas Gerais (TNMG), Brazil. Each exam was annotated using standardized diagnostic criteria and reviewed by cardiologists. A defining feature of CODE-II is a set of 66 clinically meaningful diagnostic classes, developed with cardiologist input and routinely used in telehealth practice. We additionally provide an openly available subset: CODE-II-open, a public subset of 15,000 patients, and the CODE-II-test, a non-overlapping set of 8,475 exams reviewed by multiple cardiologists for blinded evaluation. A neural network pre-trained on CODE-II achieved superior transfer performance on external benchmarks (PTB-XL and CPSC 2018) and outperformed alternatives trained on larger datasets.

Identifiers

PMID42185490
PMCPMC13519028

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.