Post-transition Care Retention and Viral Suppression Outcomes Among Youth Living with HIV in South Carolina: A Real-World Data Research.

Hao Zhang, Huiyi Xia, Fanghui Shi, Xiaoming Li, Bankole Olatosi, Sharon Weissman, Rebecca Widener, Xueying Yang

Abstract read

In one paragraph

Article in AIDS and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hao ZhangDepartment of Health Promotion, Education and Behavior, Arnold School of Public Health, University of South Carolina, 915 Greene Street, Columbia, SC, 29208, USA. hz20@email.sc.edu.ORCID http://orcid.org/0009-0000-5477-0906

Huiyi XiaDepartment of Health Promotion, Education and Behavior, Arnold School of Public Health, University of South Carolina, 915 Greene Street, Columbia, SC, 29208, USA.

Fanghui ShiDepartment of Health Promotion, Education and Behavior, Arnold School of Public Health, University of South Carolina, 915 Greene Street, Columbia, SC, 29208, USA.

Xiaoming LiDepartment of Health Promotion, Education and Behavior, Arnold School of Public Health, University of South Carolina, 915 Greene Street, Columbia, SC, 29208, USA.

Bankole OlatosiArnold School of Public Health, South Carolina SmartState Center for Healthcare Quality, University of South Carolina, Columbia, SC, 29208, USA.

Sharon WeissmanArnold School of Public Health, South Carolina SmartState Center for Healthcare Quality, University of South Carolina, Columbia, SC, 29208, USA.

Rebecca WidenerDepartment of Pediatrics, School of Medicine, University of South Carolina, Columbia, SC, 29208, USA.

Xueying YangDepartment of Health Promotion, Education and Behavior, Arnold School of Public Health, University of South Carolina, 915 Greene Street, Columbia, SC, 29208, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Youth living with HIV (YLWH) face substantial challenges following transition from pediatric to adult HIV care, yet evidence on post-transition outcomes in the Southern United States remains limited. Using statewide HIV surveillance and administrative data, we conducted a retrospective cohort study of 493 YLWH in South Carolina (SC) who transitioned to adult care between 2005 and 2021. Retention in adult care was defined as ≥ 2 viral load or CD4 tests at least 6 months apart within one year of the first adult visit, and viral suppression as a last recorded viral load < 200 copies/mL within one year. Multivariable logistic regression assessed individual- and county-level factors associated with retention in adult care and viral suppression, respectively. Overall, 52.7% of YLWH were retained in care and 49.1% achieved viral suppression one-year post-transition. Younger transition age and lower pre-transition CD4 count (≤ 200 cells/mm³) were associated with higher odds of retention in adult care, while higher pre-transition viral load (> 200 copies/mL), men who have sex with men/injecting drug use, heterosexual transmission, and higher socioeconomic vulnerability were associated with lower retention. For viral suppression, Black race, heterosexual transmission, and lower pre-transition CD4 counts were significantly associated with reduced odds of viral suppression. Post-transition outcomes among YLWH in SC remain suboptimal, highlighting the need for targeted, multilevel interventions addressing immunologic vulnerability and socioeconomic disadvantage in the Southern U.S.

Indexed as

Healthcare transitionPost-transition viral suppressionRetention in adult careSouthern United StatesStructural barriersYouth living with HIV

Identifiers

PMID42185724

DOI10.1371/journal.pone.0315866

What Socratic holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.