Evidence map›Paper›PMID 42186642›Full record

ReviewCureus2026

A Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations.

Amit Nampalliwar, Nilabh K Singh, Mohit Kher, Prashant U Sasane, Chandreshwar P Sinha, Umesh K Dixit

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amit NampalliwarDepartment Roga Nidan Evum Vikriti Vigyan (Diagnostics and Pathology), Government Ayurved College and Hospital, Bilaspur, IND.
Nilabh K SinghDepartment of Medicine, Rajendra Institute of Medical Sciences and Hospital, Ranchi, IND.
Mohit KherDepartment of Pharmacology, Kanta Devi Medical College, Hospital, and Research Centre, Mathura, IND.
Prashant U SasaneDepartment of Kayachikitsa (Internal Medicine), All India Institute of Ayurveda, Goa, IND.
Chandreshwar P SinhaDepartment of Kayachikitsa (Internal Medicine), Shri Narayan Prasad Awasthi (NPA) Government Ayurved College and Hospital, Pt. Deendayal Upadhyay Memorial Health Science and Ayush University of Chhattisgarh, Raipur, IND.
Umesh K DixitDepartment of Biochemistry, Sri Siddhi Vinayak Medical College, Sambhal, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus and prediabetes represent major global health challenges associated with metabolic and cardiovascular complications. This review was conducted to evaluate herbal medicines as complementary strategies for glycaemic control and metabolic risk reduction. This systematic review assessed the efficacy, metabolic and cardiovascular effects, and clinical safety of herbal medicines used in diabetes and prediabetes management. A systematic literature search was conducted following Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) 2020 guidelines. Eligible studies included clinical and relevant preclinical investigations reporting glycaemic, metabolic, cardiovascular, and safety outcomes of herbal interventions. Data were extracted descriptively and synthesized qualitatively due to heterogeneity in study design and outcomes. Eleven studies met the inclusion criteria. Most interventions demonstrated reductions in fasting blood glucose, postprandial glucose, oral glucose tolerance test values, and, in several cases, glycated hemoglobin. Improvements in lipid profiles and vascular parameters were also reported. Safety assessments revealed favorable tolerability, with no serious adverse events and stable hepatic and renal markers at studied doses. Findings from the included studies indicate that selected herbal medicines demonstrated adjunctive benefits in glycaemic control and metabolic parameters in diabetes and prediabetes. Further well-designed trials are needed to confirm long-term efficacy, safety, and clinical applicability.

Indexed as

diabetes mellitusglycaemic controlherbal medicinemetabolic safetyprediabetes

Identifiers

PMID42186642
PMCPMC13198626

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.