Evidence map›Paper›PMID 42187890›Full record

ArticleDiseases (Basel, Switzerland)2026

Clinical Course and Perinatal Outcomes of Pregnant Women with COVID-19 in Central Greece: A Prospective Cohort Study.

Christos Donoudis, Antonios Garas, Sotirios Sotiriou, Ioannis Pantazopoulos, Athanasios Pagonis, Eleni Zachari, Nikoletta Daponte, George Syrogiannopoulos, Ioanna Grivea, Alexandros Daponte

Abstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christos DonoudisDepartment of Obstetrics & Gynaecology, University of Thessaly, 41110 Larissa, Greece.ORCID 0000-0002-1338-1792
Antonios GarasDepartment of Obstetrics & Gynaecology, University of Thessaly, 41110 Larissa, Greece.
Sotirios SotiriouDepartment of Embryology, University of Thessaly, 41110 Larissa, Greece.
Ioannis PantazopoulosDepartment of Respiratory Medicine, University of Thessaly, 41100 Larissa, Greece.ORCID 0000-0002-8846-519X
Athanasios PagonisDepartment of Respiratory Medicine, University of Thessaly, 41100 Larissa, Greece.
Eleni ZachariIntensive Care Unit, University Hospital of Larissa, 41110 Larissa, Greece.
Nikoletta DaponteDepartment of Obstetrics & Gynaecology, University of Thessaly, 41110 Larissa, Greece.
George SyrogiannopoulosDepartment of Pediatrics, University of Thessaly, 41110 Larissa, Greece.ORCID 0000-0002-2390-3603
Ioanna GriveaDepartment of Pediatrics, University of Thessaly, 41110 Larissa, Greece.
Alexandros DaponteDepartment of Obstetrics & Gynaecology, University of Thessaly, 41110 Larissa, Greece.ORCID 0000-0001-7300-9514

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring the COVID pandemic increased rates of intensive care unit (ICU) admission, mechanical ventilation, caesarean delivery, and preterm birth among women with SARS-CoV-2 infection in pregnancy were recorded. PURPOSE: This study describes the clinical course and perinatal outcomes of pregnant women with COVID-19 across pre- and post-vaccination periods.

methodsThis study included all pregnant women with confirmed SARS-CoV-2 infection who subsequently delivered at the University General Hospital of Larissa between March 2020 and May 2023. Demographics, comorbidities, gestational age at infection and at delivery, COVID-19 symptoms, need for hospitalization, obstetric complications, mode of delivery, and neonatal outcomes were documented. An assessment of ischemia-modified albumin (IMA) was performed in a subset of women.

resultsA total of 327 women (including 14 twin gestations) were recorded. Most women experienced mild disease while a minority required hospital admission, or intensive care (1.8 and 0.3% for the studied population, respectively). Fever and upper respiratory symptoms predominated, while radiologic evidence of pneumonia was rare. Overall preterm birth (<37 weeks) occurred in 13% of pregnancies and caesarean section in about two thirds of deliveries. Neonatal outcomes were favorable, with low rates of neonatal intensive care unit (NICU) admission and no early neonatal deaths. IMA values were higher during acute infection and declined towards recovery.

conclusionPregnant women with COVID-19 in Central Greece had predominantly mild clinical courses and excellent perinatal outcomes. IMA may represent a biologically plausible marker of disease activity, but further studies are needed.

Indexed as

clinical outcomesCOVID-19ischemia-modified albuminperinatal outcomespregnancyvaccination

Identifiers

PMID42187890
PMCPMC13206536

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.