Evidence map›Paper›PMID 42188024›Full record

ArticleMetabolites2026

Association of Acylcarnitine Species and Anthropometry Markers in a Population-Based Apparently Healthy Cohort.

Ko Ko Maung, Rebecca Borreggine, Hector Gallart-Ayala, Julijana Ivanisevic, Pedro Marques-Vidal

Abstract read
In one paragraph

Article in Metabolites, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ko Ko MaungDepartment of Medicine, Internal Medicine, Lausanne University Hospital (CHUV), 1011 Lausanne, Switzerland.ORCID 0000-0002-3506-3701
Rebecca BorreggineMetabolomics Platform, Faculty of Biology and Medicine, University of Lausanne, 1015 Lausanne, Switzerland.
Hector Gallart-AyalaMetabolomics Platform, Faculty of Biology and Medicine, University of Lausanne, 1015 Lausanne, Switzerland.ORCID 0000-0003-2333-0646
Julijana IvanisevicMetabolomics Platform, Faculty of Biology and Medicine, University of Lausanne, 1015 Lausanne, Switzerland.ORCID 0000-0001-8267-2705
Pedro Marques-VidalDepartment of Medicine, Internal Medicine, Lausanne University Hospital (CHUV), 1011 Lausanne, Switzerland.ORCID 0000-0002-4548-8500

Funding

Swiss National Science Foundation grant 320030_207687
6 · The paper itself

Abstract

BACKGROUND/

objectivesAcylcarnitine has been linked to adiposity, yet evidence in healthy adults is scarce. Hence, we aim to investigate associations of circulating acylcarnitine levels with traditional and newer anthropometric markers cross-sectionally, and with future weight change prospectively.

methodsWe used data from CoLaus|PsyCoLaus cohort of apparently healthy adults in Lausanne, Switzerland. Anthropometry markers include body mass index, waist circumference, waist-hip ratio, conicity index, body roundness index, body shape index, leptin, adiponectin and grip strength.

resultsCross-sectionally, free carnitine, short-chain acylcarnitines (SCACs: C0, C3:0, C4:0 C5:0 and C5:0-OH), medium-chain acylcarnitines (MCACs: C6:0 and C8:1) and long-chain acylcarnitines (LCACs: C16:0) were positively associated with most anthropometric markers. After multivariate adjustment, only free carnitine, SCACs (C3:0 and C5:0), and MCAC C8:1 retained their positive associations with multiple markers. SCACs showed the strongest associations (-log10

conclusionsSCAC showed most consistent associations with multiple anthropometric markers. Prospectively, specific ACs were associated with weight gain, suggesting that baseline AC levels may reflect early metabolic alterations linked to adiposity.

Indexed as

acylcarnitineanthropometric markerscross-sectional studyprospective studyweight gain

Identifiers

PMID42188024
PMCPMC13208298

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.