ArticleNanomaterials (Basel, Switzerland)2026
Raman and SERS Spectra of Human Myelin Basic Protein in Cerebrospinal Fluid.
Antonio Bravo-Oro, Sergio Ugarte-Anchondo, Erick Osvaldo Martínez-Ruiz, Ma Del Carmen Rodríguez-Aranda, Adán Reyes-Reyes, Cristian Israel García-Mendoza, Luis Carlos Ortiz-Dosal, Emmanuel Rivera-Pérez, Juan Andrés Reyes-Reyes, Eleazar Samuel Kolosovas-Machuca and 1 more
Abstract read
In one paragraphArticle in Nanomaterials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Antonio Bravo-OroPediatric Neurology Department, Hospital Regional de Alta Especialidad Dr. Ignacio Morones Prieto, Av. Niño Artillero 141, San Luis Potosí 78240, Mexico.ORCID 0000-0003-4787-5632 Sergio Ugarte-AnchondoPediatric Neurology Department, Hospital Regional de Alta Especialidad Dr. Ignacio Morones Prieto, Av. Niño Artillero 141, San Luis Potosí 78240, Mexico.ORCID 0000-0002-3731-2791 Erick Osvaldo Martínez-RuizCoordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí, Av. Sierra Leona 550, San Luis Potosí 78210, Mexico.
Ma Del Carmen Rodríguez-ArandaCoordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí, Av. Sierra Leona 550, San Luis Potosí 78210, Mexico.ORCID 0000-0003-0632-2265 Adán Reyes-ReyesFacultad de Ciencias, Universidad Autónoma de San Luis Potosí, Av. Parque Chapultepec 1570, San Luis Potosí 78295, Mexico.ORCID 0009-0003-3261-1770 Cristian Israel García-MendozaFacultad de Ciencias, Universidad Autónoma de San Luis Potosí, Av. Parque Chapultepec 1570, San Luis Potosí 78295, Mexico.ORCID 0009-0009-0390-1318 Luis Carlos Ortiz-DosalMaestría en Ciencia e Ingeniería de los Materiales (MCIM-UAZ), Universidad Autónoma de Zacatecas, 801 López Velarde St. 9800, Zacatecas 98160, Mexico.ORCID 0000-0002-3685-9808 Emmanuel Rivera-PérezCoordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí, Av. Sierra Leona 550, San Luis Potosí 78210, Mexico.
Juan Andrés Reyes-ReyesCoordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí, Av. Sierra Leona 550, San Luis Potosí 78210, Mexico.ORCID 0009-0002-3397-3311 Eleazar Samuel Kolosovas-MachucaCoordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí, Av. Sierra Leona 550, San Luis Potosí 78210, Mexico.ORCID 0000-0002-7583-8655 Alejandra Ortiz-DosalFacultad de Ciencias UASLP-SECIHTI, Av. Parque Chapultepec 1570, San Luis Potosí 78295, Mexico.ORCID 0000-0002-0536-4394 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Raman spectroscopy (RS) provides detailed information on molecular structure but remains challenging for low-scattering proteins in complex media. Myelin basic protein (MBP) is a key structural component of central nervous system myelin and a clinically relevant molecule in demyelinating disorders; however, to the best of our knowledge, its Raman signature in solution has not been reported. In this work, Raman and surface-enhanced Raman spectroscopy (SERS) were employed to characterize purified human myelin basic protein (MBP) in aqueous solution and cerebrospinal fluid (CSF). Quasi-spherical silver nanoparticles were used as SERS elements, yielding enhancement factors of 10
Indexed as
biomarkersmyelin disordersspectral analysisvibrational spectroscopy
Identifiers
PMID42188489
PMCPMC13209463
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390