Trial reportJMIR mHealth and uHealth2026
Reducing Sedentary Time After Knee Replacement Using a Multicomponent mHealth Intervention: Randomized Controlled Trial.
Trial report in JMIR mHealth and uHealth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04482400 (Reducing Sedentary Time Using an Innovative mHealth Intervention Among Total Knee Replacement Patients), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Reducing Sedentary Time Using an Innovative mHealth Intervention Among Total Knee Replacement Patients
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTotal knee replacement (TKR) is a common surgery for end-stage knee osteoarthritis. Although reductions in pain and improvements in mobility occur after surgery, physical activity levels often do not change. Given the challenges of increasing physical activity in this population, targeting reductions in sedentary behavior may be a first step; however, no prior studies have examined the feasibility and effects of a sedentary reduction intervention after TKR.
objectiveThis study examined the effects of a 2-month multicomponent mobile health sedentary reduction intervention (NEAT!2) on sedentary time in adults with TKR.
methodsAdults (N=83; mean age 65.3, SD 9.4 years; mean BMI 32.7, SD 6.9 kg/m
resultsRetention was 96% and 95% at 2 and 5 months, respectively, with no differences between groups. Participants in the NEAT!2 group completed an average of 4.95 (SD 0.2) calls, used the app on an average of 40.3 (SD 13.8) days (out of 56 days), and received an average of 9.6 (SD 6.0) notifications per day. At 5 months, there was a significant increase in sit-to-stand transitions in the NEAT!2 group and a substantial decrease in the control group, resulting in a significant difference between groups (mean difference 4.06, 95% CI 0.13-7.99; P=.04); however, the NEAT!2 intervention did not result in significant effects on any of the other study outcomes at 2 or 5 months. Additionally, more days of app use were associated with greater increases in moderate-to-vigorous intensity physical activity (r=0.335; 95% CI 0.017-0.585; P=.04).
conclusionsThis study highlights the challenges of reducing sitting time in adults with TKR. Future studies should explore alternative behavior change techniques across different levels of influence (eg, environmental and social) to support interventions implemented within the first year after TKR.
trial registrationClinicalTrials.gov NCT04482400; https://clinicaltrials.gov/ct2/show/NCT04482400.
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