ReviewDie Ophthalmologie2026
[Vitreous body substitutes: current solutions and future perspectives].
Review in Die Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe human vitreous body plays an important role in intraocular homeostasis and fulfils structural, metabolic and immunological functions. In the context of vitreoretinal surgery artificial endotamponades are introduced to stabilize the retina.
objectiveClinically established endotamponades, their applications, advantages and disadvantages, the distinction from total vitreous body replacement and the development of hydrophilic vitreous body substitutes are presented. The current state of development and the potential of synthetic hydrogels as vitreous body substitutes are analyzed. MATERIAL AND
methodsDiscussion of the basic literature and review articles on surgical endotamponades and hydrogel-based vitreous body substitutes.
resultsAll established endotamponades exert a local stabilizing function through the principle of buoyancy or counterbuoyancy combined with surface tension and show disadvantages for the patient. Vitreous body substitutes, which can fully replace the physiological functions of the natural vitreous body, must be distinguished from endotamponades. The development of hydrogels has progressed through four generations, each offering promising approaches.
conclusionThere are promising solutions involving synthetic hydrogels that could undertake and even expand the physiological role of the vitreous body as vitreous body substitutes, thereby improving therapeutic outcomes and patient satisfaction.
Indexed as
Identifiers
42191908What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.