Evidence map›Paper›PMID 42193250›Full record

ReviewAntioxidants (Basel, Switzerland)2026

Phyllobilins: Emerging Bioactive Chlorophyll Metabolites and Their Potential Impact on Human Health.

María Del Rosario Serra, Antonio Pérez-Gálvez, María Roca

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

María Del Rosario SerraGroup of Chemistry and Biochemistry of Pigments, Food Phytochemistry Department, Instituto de la Grasa (CSIC), 41013 Sevilla, Spain.ORCID 0009-0009-6550-7789
Antonio Pérez-GálvezGroup of Chemistry and Biochemistry of Pigments, Food Phytochemistry Department, Instituto de la Grasa (CSIC), 41013 Sevilla, Spain.ORCID 0000-0001-6914-8378
María RocaGroup of Chemistry and Biochemistry of Pigments, Food Phytochemistry Department, Instituto de la Grasa (CSIC), 41013 Sevilla, Spain.ORCID 0000-0003-3681-9846

Funding

Agencia Estatal de Investigación MCIN/AEI/10.13039/501100011033Consejo Superior de Investigaciones Científicas PIE 202370E176
6 · The paper itself

Abstract

Phyllobilins are chlorophyll metabolites that belong to bilin-type linear tetrapyrroles. Chlorophyll, the omnipresent green pigment from algae to higher plants, is essential for life on Earth, underscoring the significance of its metabolites among phytochemicals. Once largely overlooked, phyllobilins are now gaining recognition for their widespread presence in the human diet through the consumption of fruits and vegetables. This, together with their favorable bioavailability, has heightened the importance of elucidating their bioactive properties. Numerous studies have demonstrated their antioxidant and anticancer activities in vitro, as well as their ability to target actin. The anti-inflammatory effects of phyllobilins have also been demonstrated by evaluating their ability to inhibit the COX-2 pathway or attenuate the activation of the tryptophan-kynurenine pathway. The objective of this review is to highlight the value of phyllobilins by compiling current knowledge, with a particular emphasis on their bioactivity and potential impact on human health.

Indexed as

anticanceranti-inflammatoryantioxidantbioactivitychlorophyllhealthmetabolismphyllobilinsphytochemicals

Identifiers

PMID42193250
PMCPMC13203533

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.