ReviewBiomolecules2026
Rewiring Adipocyte Plasticity: The Redox-Mitochondrial Axis as a Driver of Beige Fat Immunometabolism and Adipose Inflammation.
Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Obesity is a major health crisis that impacts social and economic burdens worldwide, and it is being studied intensively to understand the molecular mechanisms and regulators of this complex condition. Over the past decade, significant insights into adipocyte fate have been gained, demonstrating that adipocyte behavior is influenced by intracellular pathways, systemic mediators, and environmental signals. In this review, we discuss the current understanding of key molecular and functional changes in adipose tissue. We focused on ER-mitochondrial dynamics and their role in beige adipocytes. We examined the biological properties of beige fat cells, including their inflammatory status, redox balance, and regulation of adipocyte transdifferentiation via signaling molecules. Finally, we explored the effects of naturally derived compounds on adipocyte function and their potential to combat obesity using a comprehensive approach. The process of adipocyte beiging induced by coordinated intracellular signaling pathways highlights mechanisms that can reprogram metabolic homeostasis and reduce obesity-related phenotypes.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.