Longitudinal Blood Epigenetic Aging, DNA Methylation-Predicted Protein, and Estimated Leukocyte Proportion Trends in Two Astronauts from the Axiom Space Mission 1: An Exploratory Analysis.

Jamaji C Nwanaji-Enwerem, Dennis Khodasevich, Jermaine Blakley, Jonathan M Galazka, Andres Cardenas

Abstract read

In one paragraph

Article in Genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jamaji C Nwanaji-EnweremDepartment of Emergency Medicine, Center for Health Justice, Center of Excellence in Environmental Toxicology, Perelman School of Medicine, University of Pennsylvania, Ground Ravdin, HUP, 3400 Spruce Street, Philadelphia, PA 19104, USA.ORCID 0000-0003-0356-4867

Dennis KhodasevichDepartment of Epidemiology and Population Health, Stanford University, Palo Alto, CA 94305, USA.

Jermaine BlakleyCollege of Medicine, Howard University, Washington, DC 20059, USA.

Jonathan M GalazkaSpace Biosciences Division, NASA Ames Research Center, Moffett Field, CA 94035, USA.ORCID 0000-0002-4153-0249

Andres CardenasDepartment of Epidemiology and Population Health, Stanford University, Palo Alto, CA 94305, USA.ORCID 0000-0003-2284-3298

Funding

NIH HHS R01ES031259

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgingAstronautsDNA MethylationEpigenesis, GeneticLeukocytesBiomarkersHumansSpace FlightBiomarkersDNA methylationimmune cell dynamicsmicrogravityproteomic signatures

Identifiers

PMID42195021

DOI10.3390/genes17050564

PMCPMC13206426

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.