Evidence mapPaperPMID 42196096Full record

ReviewGels (Basel, Switzerland)2026

Cellulose-Based Hydrogels for Chronic Wound Healing: Bridging Biomaterial Design and Clinical Unmet Needs.

Irina Negut, Anita Ioana Visan

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Irina NegutNational Institute for Laser, Plasma and Radiation Physics (INFLPR), Atomistilor 409, 077125 Magurele, Romania.ORCID 0000-0003-4038-7548
Anita Ioana VisanNational Institute for Laser, Plasma and Radiation Physics (INFLPR), Atomistilor 409, 077125 Magurele, Romania.ORCID 0000-0003-0539-4160

Funding

Romanian Educational and Research Network project number PN-IV-P7-7.1-PED-2024-0137Romanian Educational and Research Network Romanian National Nucleu Program LAPLAS VII-contract No. 30N/2023
6 · The paper itself

Abstract

Chronic wounds remain a persistent clinical challenge, trapped in a cycle of inflammation, infection, and impaired healing. While traditional dressings offer basic protection, they fail to address the complex pathophysiology of non-healing wounds. This review critically examines cellulose-based hydrogels as next-generation therapeutic platforms, analyzing their structure-property relationships, biofunctionalization strategies, and stimuli-responsive capabilities. We synthesize recent advances in antimicrobial, anti-inflammatory, and pro-regenerative hydrogels, highlighting how cellulose's inherent tunability enables precision wound management. Finally, we confront the translational barriers-including scalability, sterilization, and regulatory hurdles-that must be overcome to bridge the gap between promising biomaterial research and clinical reality. By integrating materials science with wound pathophysiology, this review provides a roadmap for developing clinically viable cellulose-based hydrogels.

Indexed as

antimicrobial hydrogelsbacterial cellulosecellulose hydrogelschronic woundssmart biomaterialsstimuli-responsive materialstissue regenerationwound dressings

Identifiers

PMID42196096
PMCPMC13206090

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.