Evidence map›Paper›PMID 42196261›Full record

ArticleInternational journal of molecular sciences2026

Computational Analysis of SPI1 Missense Mutations and ADMET-Guided Molecular Docking of Cinnamic Acid Targeting the PU.1 ETS Domain: Implications for Hematopoietic Dysregulation and Leukemogenesis.

Mariam M Jaddah, Samer N Khalaf, Mohammed Mukhles Ahmed, Aisha Abdullah Alshanqiti

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Multi-Omics Analysis of the Effects ofInternational journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mariam M JaddahDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Al Madinah Al Munawarah 42353, Saudi Arabia.ORCID 0009-0007-6120-2748
Samer N KhalafDepartment of Biotechnology, College of Science, University of Anbar, Ramadi 31001, Iraq.ORCID 0000-0001-7459-6474
Mohammed Mukhles AhmedDepartment of Biotechnology, College of Science, University of Anbar, Ramadi 31001, Iraq.ORCID 0000-0002-2831-9246
Aisha Abdullah AlshanqitiDepartment of Physiology, College of Medicine, Umm Al-Qura University, P.O. Box 715, Makkah 24382, Saudi Arabia.ORCID 0009-0000-9704-6723

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spi-1 Proto-Oncogene (

Indexed as

HematopoiesisLeukemia, Myeloid, AcuteMolecular Docking SimulationMutation, MissenseProto-Oncogene ProteinsTrans-ActivatorsAnimalsHumansProtein DomainsProto-Oncogene MasProto-Oncogene Protein Spi-1MAS1 protein, humanProto-Oncogene MasProto-Oncogene ProteinsProto-Oncogene Protein Spi-1Trans-ActivatorsAMLCinnamic acidETS domainhematopoiesisin silico bioinformaticsmissense nsSNPsprotein structureSPI1TCGAtranscription factors

Identifiers

PMID42196261
PMCPMC13206789

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.