ArticleInternational journal of molecular sciences2026
Integrative sRNA, DNA Methylation, and Transcriptomics Reveals Dynamic Epigenetic Reprogramming of
Jose Domínguez-Figueroa, Ana Cláudia Silva, Patricia Abril-Urias, Sebastian Y Müller, Maria Jose Ladera-Carmona, Patrick Schäfer, Victoria Baca-González, Elena Caro, Carolina Escobar
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
9 authors.
Jose Domínguez-FigueroaFacultad de Ciencias Ambientales y Bioquímica, Universidad de Castilla-La Mancha, E-45071 Toledo, Spain.
Ana Cláudia SilvaFundación FUNDECYT (Fundación para el Desarrollo de la Ciencia y la Tecnología)-Parque Científico y Tecnológico de Extremadura, Avda. de Elvas s/n, 06006 Badajoz, Spain.
Patricia Abril-UriasFacultad de Ciencias Ambientales y Bioquímica, Universidad de Castilla-La Mancha, E-45071 Toledo, Spain.
Maria Jose Ladera-CarmonaInstitute of Phytopathology, Centre for BioSystems, Land Use and Nutrition, Justus Liebig University, Heinrich-Buff-Ring 26, 35392 Giessen, Germany.ORCID 0000-0003-2167-3135 Patrick SchäferInstitute of Phytopathology, Centre for BioSystems, Land Use and Nutrition, Justus Liebig University, Heinrich-Buff-Ring 26, 35392 Giessen, Germany.ORCID 0000-0002-0366-6858 Victoria Baca-GonzálezCentro de Biotecnología y Genómica de Plantas (CBGP), Universidad Politécnica de Madrid and Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria-Consejo Superior de Investigaciones Científicas (UPM-INIA/CSIC), Campus de Montegancedo, 28223 Madrid, Spain.ORCID 0000-0001-7195-7211 Elena CaroCentro de Biotecnología y Genómica de Plantas (CBGP), Universidad Politécnica de Madrid and Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria-Consejo Superior de Investigaciones Científicas (UPM-INIA/CSIC), Campus de Montegancedo, 28223 Madrid, Spain.ORCID 0000-0002-1034-1621 Carolina EscobarFacultad de Ciencias Ambientales y Bioquímica, Universidad de Castilla-La Mancha, E-45071 Toledo, Spain.ORCID 0000-0001-9365-0851 Funding
Castilla-La Mancha Government and the UE FEDER SBPLY/21/180501/000033 and SBPLY/24/180225/000017EU HORIZON-RIA, HORIZON-CL6-202 FARM2FORK 02-two-stage 101083727-NEM-EMERGEMICIU/AEI/10.13039/501100011033 and FEDER, UE PID2022-138989OB-I00 and RED2024-153709-T
6 · The paper itselfAbstract
Root knot nematodes (RKNs) induce galls, containing multinucleated giant cells (GCs) to nourish them. The differentiation of precursor cells to galls/GCs involves extensive cellular reprogramming with multiple layers of regulation. Epigenetic regulation during the early stages of infection indicates that RNA-directed DNA methylation (RdDM) and microRNA-dependent gene silencing contribute to transcriptional and post-transcriptional reprogramming during gall organogenesis. Although later stages of galls/GC development are crucial for nematode life-cycle maintenance, epigenetic reprogramming events remain largely unexplored. An integrative analysis of sRNAs, DNA methylation, and transcriptomic dynamics in galls induced by
Indexed as
ArabidopsisDNA MethylationEpigenesis, GeneticPlant TumorsRNA, Small UntranslatedTranscriptomeTylenchoideaAnimalsGene Expression ProfilingGene Expression Regulation, PlantMicroRNAsMicroRNAsRNA, Small UntranslatedDNA methylationmiRNAsrasiRNAsroot-knot nematodessRNAstranscriptomics
Identifiers
PMID42196344
PMCPMC13207400
What Socratic holds
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LicenceCC BY
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