ArticleInternational journal of molecular sciences2026
Detection of Oral Bacterial DNA in Abdominal Aortic Aneurysm and Its Microbial Associations.
Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
Abdominal aortic aneurysm (AAA) is a life-threatening disease for which no definitive medical therapy has been established, partly because its underlying mechanisms remain incompletely understood. Given accumulating evidence suggesting microbial involvement in vascular inflammation, we conducted a detection-based investigation to identify bacterial DNA in aneurysmal tissues. We performed 16S ribosomal RNA (rRNA) gene sequencing of the aneurysmal wall, intraluminal thrombus, feces, saliva, and dental plaque collected from 32 patients undergoing open surgical repair of non-infectious AAA. Based on the sequencing data, diversity analyses were performed for each sample to characterize bacterial composition, and exploratory statistical analyses were conducted to examine associations between patient characteristics and the relative abundance of bacterial taxa. Oral-associated genera were frequently detected in aneurysm-derived samples, including
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