Decoding Isoprenoid Transcript-Metabolite Interactions in Carotenoid Tomato Fruit Mutants Uncovers Novel Metabolic Cross-Links.

Sarah Frusciante, Olivia Costantina Demurtas, Giulia Falcone, Giovanni Giuliano, Gianfranco Diretto

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sarah FruscianteCasaccia Research Centre, Department for Sustainability, Italian National Agency for New Technologies, Energy and Sustainable Development (ENEA), Via Anguillarese 301, 00123 Rome, Italy.ORCID 0000-0001-8161-3797

Olivia Costantina DemurtasCasaccia Research Centre, Department for Sustainability, Italian National Agency for New Technologies, Energy and Sustainable Development (ENEA), Via Anguillarese 301, 00123 Rome, Italy.ORCID 0000-0003-3344-5754

Giulia FalconeCasaccia Research Centre, Department for Sustainability, Italian National Agency for New Technologies, Energy and Sustainable Development (ENEA), Via Anguillarese 301, 00123 Rome, Italy.

Giovanni GiulianoCasaccia Research Centre, Department for Sustainability, Italian National Agency for New Technologies, Energy and Sustainable Development (ENEA), Via Anguillarese 301, 00123 Rome, Italy.

Gianfranco DirettoCasaccia Research Centre, Department for Sustainability, Italian National Agency for New Technologies, Energy and Sustainable Development (ENEA), Via Anguillarese 301, 00123 Rome, Italy.ORCID 0000-0002-1441-0233

Funding

European Council 101182796European Union 101158453

6 · The paper itself

Abstract

Carotenoids are an important class of natural compounds, essential for human nutrition, acting in plants as pigments and apocarotenoid precursors. Tomato is a key model for carotenoid metabolism, as genetic variation strongly affects carotenoid composition during fruit ripening. To date, most of the enzymes involved in the carotenoid pathway were mainly characterized by linking gain- or loss-of-function phenotypes to their genetic basis (e.g., mutation in a single gene), with limited integration into pathway-wide analyses. Here we report an extensive biochemical and molecular characterization of a collection of tomato carotenoid mutants-

Indexed as

CarotenoidsFruitMutationSolanum lycopersicumTerpenesGene Expression ProfilingGene Expression Regulation, PlantMetabolomicsCarotenoidsTerpenescarotenoid biosynthesiscorrelation analysisfruit ripeningisoprenoidsmetabolomicstomatotranscriptomics

Identifiers

PMID42196389

DOI10.3390/ijms27104412

PMCPMC13207119

What Socratic holds

Textmetadata

LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.