Evidence mapPaperPMID 42196534Full record

ArticleInternational journal of molecular sciences2026

Network Pharmacology Reveals the Therapeutic Potential of BBB-Permeable Compounds from

Jiayi He, Jihong Li, Junwei Huo, Yijun Pang, Kaiqi Sun, Haoyu Zhu, Yuhan He, Zhixuan Ren, Xin Cheng, Shuang Ao and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jiayi HeDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150086, China.ORCID 0009-0000-6906-7607
Jihong LiDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150086, China.ORCID 0000-0001-5221-0104
Junwei HuoKey Laboratory of Biology and Genetic Improvement of Horticultural Crops (Northeast Region), Ministry of Agriculture and Rural Affairs, College of Horticulture and Landscape Architecture, Northeast Agricultural University, Harbin 150030, China.ORCID 0000-0002-0064-8697
Yijun PangDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150086, China.
Kaiqi SunDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150086, China.
Haoyu ZhuDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150086, China.
Yuhan HeDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150086, China.
Zhixuan RenDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150086, China.
Xin ChengDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150086, China.
Shuang AoDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150086, China.
Yahui PengDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150086, China.ORCID 0009-0006-6076-9796

Funding

Key Project of "14th Five-Year" Plan for Heilongjiang Provincial Educational Science Research in 2025 GJB1425362Key R&D Program of China 2022YFD1600500Special Support Program for "Excellent Physician Training Research" of Harbin Medical Univer-sity in 2025 N/Athe Industry-University Co-operation Project of the Natural Science Foundation of Heilongjiang Province JJ2025XQ0159the Key Research and Development Program of Heilongjiang Province GZ20040050
6 · The paper itself

Abstract

Although risk factors for Alzheimer's disease (AD) involve obesity and elevated low-density lipoprotein (LDL) cholesterol levels, and

Indexed as

Alzheimer DiseaseBlood-Brain BarrierLipid Metabolism DisordersLoniceraPlant ExtractsHumansLipid MetabolismMolecular Docking SimulationMolecular Dynamics SimulationNetwork PharmacologyPlant ExtractsAlzheimer’s diseaselipid metabolism disordersLonicera caeruleaMendelian randomizationmolecular dockingmolecular dynamics simulationnetwork pharmacology

Identifiers

PMID42196534
PMCPMC13208057

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.