Evidence map›Paper›PMID 42196913›Full record

ReviewDiagnostics (Basel, Switzerland)2026

Fibroblast Activation Protein Inhibitor (FAPI) PET: A Scoping Review of Emerging Oncologic and Fibroinflammatory Applications.

Emmanouil Panagiotidis, Filippos Koinis, Jules Zhang-Yin, George Angelidis, Varvara Valotassiou, Ioannis Tsougos, Athanasios Kotsakis, Panagiotis Georgoulias

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emmanouil PanagiotidisNuclear Medicine Laboratory, University Hospital of Larissa, 413 34 Larissa, Greece.ORCID 0000-0002-8501-3905
Filippos KoinisDepartment of Medical Oncology, University Hospital of Larissa, 413 34 Larissa, Greece.ORCID 0000-0001-5495-3331
Jules Zhang-YinDepartment of Nuclear Medicine, Clinique Sud Luxembourg, Vivalia, 6700 Arlon, Belgium.ORCID 0000-0001-8451-2094
George AngelidisNuclear Medicine Laboratory, University Hospital of Larissa, 413 34 Larissa, Greece.
Varvara ValotassiouNuclear Medicine Laboratory, University Hospital of Larissa, 413 34 Larissa, Greece.ORCID 0000-0001-8439-6708
Ioannis TsougosMedical Physics Laboratory, University Hospital of Larissa, 413 34 Larissa, Greece.ORCID 0000-0002-5204-5273
Athanasios KotsakisDepartment of Medical Oncology, University Hospital of Larissa, 413 34 Larissa, Greece.ORCID 0000-0002-5530-6774
Panagiotis GeorgouliasNuclear Medicine Laboratory, University Hospital of Larissa, 413 34 Larissa, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This scoping review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) guidelines. It summarizes advances in fibroblast activation protein inhibitor (FAPI) positron emission tomography (PET) for oncologic and fibroinflammatory diseases. FAP is expressed broadly on activated mesenchymal cells-including cancer-associated fibroblasts (CAFs) and myofibroblasts within desmoplastic tumor stroma, FAP-positive tumor cells in selected sarcomas, and activated fibroblasts in chronic fibroinflammatory disorders such as rheumatoid arthritis, Crohn's disease, and organ fibrosis. By targeting these activated fibroblasts, [

Indexed as

artificial intelligencecancer-associated fibroblasts (CAFs)fibroblast activation protein inhibitor (FAPI)PET/CTPRISMA-ScRstandardized imaging protocolstheranostics

Identifiers

PMID42196913
PMCPMC13206015

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.