Trial reportNutrients2026
Effect of Knowledge of Personal Metabolic-Trait SNP Genotypes with Tailored Lifestyle Recommendations on Body Weight and Body Composition: A Randomized Controlled Trial.
Trial report in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesCommunicating genetic risk has been proposed as a motivational tool for weight control, but evidence remains limited.
methodsWe conducted a randomized controlled trial among 53 overweight or obese young adults in South Korea. Participants were randomized to receive either their obesity-related genetic results with tailored lifestyle recommendations (intervention,
resultsOverall, body weight and composition changes did not differ significantly between groups at 6 or 18 months. In exploratory subgroup analysis conducted among participants with obesity-related genetic risk, body weight increased in the intervention group (model-adjusted mean change, 2.68 kg; 95% CI, 2.28 to 3.09) but decreased in the control group (model-adjusted mean change, -11.58 kg; 95% CI, -1.99 to -1.18) over 18 months. Among participants with obesity-related genetic risk in the intervention group, those who reported behavior changes after receiving their genetic test results experienced modest weight reductions over 6 months compared with non-changers.
conclusionsDisclosure of obesity-related genetic information with tailored advice did not improve weight outcomes overall, but may benefit a subset of genetically susceptible individuals. Larger trials are warranted.
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