Evidence mapPaperPMID 42197219Full record

ArticleMolecules (Basel, Switzerland)2026

Edible Natural Deep Eutectic Solvents (NADESs)-Based Polyphenolic Extracts: An Eco-Sustainable Alternative for Grape Pomace Valorization.

Vincenzo Roselli, Rosalba Leuci, Marco Paparella, Gianluca Pugliese, Carlos Luz, Alessandra Cimbalo, Lara Manyes, Luigi Tarricone, Vincenzo Tufarelli, Lucia Gambacorta and 2 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Vincenzo RoselliDepartment of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Campus E. Quagliariello, Via E. Orabona, 4, 70126 Bari, BA, Italy.ORCID 0009-0007-2910-9359
Rosalba LeuciDepartment of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Campus E. Quagliariello, Via E. Orabona, 4, 70126 Bari, BA, Italy.ORCID 0000-0002-5229-988X
Marco PaparellaDepartment of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Campus E. Quagliariello, Via E. Orabona, 4, 70126 Bari, BA, Italy.ORCID 0009-0000-9744-3606
Gianluca PuglieseDepartment of Precision and Regenerative Medicine and Jonian Area (DiMePRe-J), Section of Veterinary Science and Animal Production, University of Bari Aldo Moro, 70010 Valenzano, BA, Italy.ORCID 0009-0004-7674-9947
Carlos LuzDepartment Food Science and Toxicology, Faculty of Pharmacy, University of Valencia, Ave. Vicent Andrés Estellés 22, 46100 Burjassot, Spain.ORCID 0000-0002-6922-3064
Alessandra CimbaloDepartment Food Science and Toxicology, Faculty of Pharmacy, University of Valencia, Ave. Vicent Andrés Estellés 22, 46100 Burjassot, Spain.ORCID 0000-0002-4741-3967
Lara ManyesDepartment Food Science and Toxicology, Faculty of Pharmacy, University of Valencia, Ave. Vicent Andrés Estellés 22, 46100 Burjassot, Spain.ORCID 0000-0001-5777-6107
Luigi TarriconeResearch Centre for Viticulture and Enology, Council for Agricultural Research and Agricultural Economy Analysis (CREA-VE), Via Casamassima, 148, 70010 Turi, BA, Italy.ORCID 0000-0002-6186-430X
Vincenzo TufarelliDepartment of Precision and Regenerative Medicine and Jonian Area (DiMePRe-J), Section of Veterinary Science and Animal Production, University of Bari Aldo Moro, 70010 Valenzano, BA, Italy.ORCID 0000-0003-0089-4393
Lucia GambacortaInstitute of Science of Food Production (ISPA), Research National Council (CNR), Via Amendola, 122/O, 70126 Bari, BA, Italy.ORCID 0000-0002-8870-8198
Giuseppe MecaDepartment Food Science and Toxicology, Faculty of Pharmacy, University of Valencia, Ave. Vicent Andrés Estellés 22, 46100 Burjassot, Spain.
Luca PiemonteseDepartment of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Campus E. Quagliariello, Via E. Orabona, 4, 70126 Bari, BA, Italy.ORCID 0000-0002-7980-5818

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reusing waste materials is a sustainable practice to reduce the impact of human activities on the global ecosystem. In particular, agro-industrial waste can be explored as an innovative and green source of beneficial bioactive compounds. For this purpose, seventeen different varieties of wine grape pomace were collected from the Apulia region (Italy) to perform extractions and qualitative-quantitative phenolic profile characterization. To ensure an environmentally friendly extraction process, natural deep eutectic solvents (NADESs) were used as privileged media. After an initial screening,

Indexed as

Deep Eutectic SolventsPlant ExtractsPolyphenolsVitisAntioxidantsAscorbic AcidBetaineCholineAntioxidantsAscorbic AcidBetaineCholineDeep Eutectic SolventsPlant ExtractsPolyphenolsbioactive moleculesgrape pomaceHPLC-DADmetabolomicsNADESs

Identifiers

PMID42197219
PMCPMC13209698

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.