Evidence map›Paper›PMID 42199656›Full record

ArticleInternational journal of nanomedicine2026

Hollow Cu

Feixiao Ma, Anqi Ji, Beng Ma, Pingjuan Yang, Jiayi Li, Shuxin Liao, Haonan Yao, Xuanhu Xie, Zhiwei Wang, Linlin Shi and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Feixiao Ma *Kaifeng Key Laboratory of Precision Diagnosis and Treatment for Oncology, The First Affiliated Hospital of Henan University, Henan University, Kaifeng, 475000, People's Republic of China.
Anqi Ji *School of Materials Science and Engineering, The First Affiliated Hospital of Henan University of Science and Technology, Henan University of Science and Technology, Luoyang, 471023, People's Republic of China.
Beng MaDepartment of Chemistry, Department of Orthopedic Trauma and Microsurgery of Zhongnan Hospital, Key Laboratory of Biomedical Polymers of Ministry of Education, Wuhan University, Wuhan, 430072, People's Republic of China.
Pingjuan YangHenan Key Laboratory of Microbiome and Esophageal Cancer Prevention and Treatment, Henan Key Laboratory of Cancer Epigenetics, The First Affiliated Hospital of Henan University of Science and Technology, Henan University of Science and Technology, Luoyang, 471023, People's Republic of China.
Jiayi LiHenan Key Laboratory of Microbiome and Esophageal Cancer Prevention and Treatment, Henan Key Laboratory of Cancer Epigenetics, The First Affiliated Hospital of Henan University of Science and Technology, Henan University of Science and Technology, Luoyang, 471023, People's Republic of China.
Shuxin LiaoHenan Key Laboratory of Microbiome and Esophageal Cancer Prevention and Treatment, Henan Key Laboratory of Cancer Epigenetics, The First Affiliated Hospital of Henan University of Science and Technology, Henan University of Science and Technology, Luoyang, 471023, People's Republic of China.
Haonan YaoSchool of Materials Science and Engineering, The First Affiliated Hospital of Henan University of Science and Technology, Henan University of Science and Technology, Luoyang, 471023, People's Republic of China.
Xuanhu XieKaifeng Key Laboratory of Precision Diagnosis and Treatment for Oncology, The First Affiliated Hospital of Henan University, Henan University, Kaifeng, 475000, People's Republic of China.
Zhiwei WangKaifeng Key Laboratory of Precision Diagnosis and Treatment for Oncology, The First Affiliated Hospital of Henan University, Henan University, Kaifeng, 475000, People's Republic of China.
Linlin ShiHenan Key Laboratory of Microbiome and Esophageal Cancer Prevention and Treatment, Henan Key Laboratory of Cancer Epigenetics, The First Affiliated Hospital of Henan University of Science and Technology, Henan University of Science and Technology, Luoyang, 471023, People's Republic of China.
Shegan GaoHenan Key Laboratory of Microbiome and Esophageal Cancer Prevention and Treatment, Henan Key Laboratory of Cancer Epigenetics, The First Affiliated Hospital of Henan University of Science and Technology, Henan University of Science and Technology, Luoyang, 471023, People's Republic of China.
Xin HouKaifeng Key Laboratory of Precision Diagnosis and Treatment for Oncology, The First Affiliated Hospital of Henan University, Henan University, Kaifeng, 475000, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Esophageal cancer (EC) ranks among the most prevalent and lethal malignancies worldwide, and conventional therapeutic modalities, including surgery, radiotherapy, and chemotherapy, are constrained by inherent limitations. Recent advances in nanomedicine have opened new avenues for EC treatment. To achieve efficient and precise tumor eradication, this study developed a pH-responsive composite nanoplatform featuring a hollow architecture to enable high-efficiency loading of photosensitizers and realize multimodal synergistic therapy against EC through the integration of photothermal therapy (PTT), photodynamic therapy (PDT), and chemodynamic therapy (CDT). Methods: A pH-responsive Cu Results: The hollow Cu Conclusion: Hollow Cu

Indexed as

Esophageal NeoplasmsIndolesNanoparticlesPhotosensitizing AgentsPolymersAnimalsApoptosisCell Line, TumorCell SurvivalCombined Modality TherapyCopperHumansHydrogen-Ion ConcentrationMicePhotochemotherapyReactive Oxygen Species2-(2-(2-chloro-3-((1,3-dihydro-3,3-dimethyl-1-propyl-2H-indol-2-ylidene)ethylidene)-1-cyclohexen-1-yl)ethenyl)-3,3-dimethyl-1-propylindoliumCopperIndolesPhotosensitizing AgentspolydopaminePolymersReactive Oxygen SpeciesSeleniumCu2-xSe/PDA/IR820esophageal cancer treatmenthollow porousmultimodal synergistic treatmentPH-responsive

Identifiers

PMID42199656
PMCPMC13199874

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.