Evidence mapPaperPMID 42199745Full record

ArticleFrontiers in nutrition2026

Association of cholesterol, high-density lipoprotein, and glucose (CHG) index with chronic kidney disease in Chinese community adults: findings from the REACTION study.

Xue Bai, Zujiao Wu, Qiuqing Wang, Ying Miao, Zhihong Zhang, Lilan Liu, Wei Huang, Fangyuan Teng, Yong Xu, Qin Wan and 1 more

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Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Xue Bai *Department of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Zujiao Wu *Department of Clinical Nutrition, Chengdu Eighth People's Hospital (Geriatric Hospital of Chengdu Medical College), Chengdu, China.
Qiuqing Wang *Department of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Ying MiaoDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Zhihong ZhangDepartment of General Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Lilan LiuDepartment of Endocrinology, Hejiang People's Hospital, Luzhou, China.
Wei HuangDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Fangyuan TengDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Yong XuDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Qin WanDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Pijun YanDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Luzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: While a limited-scale study in Turkey identified an association between the cholesterol, high-density lipoprotein, and glucose (CHG) index and diabetic nephropathy, evidence on the relationship between the CHG index and chronic kidney disease (CKD) is lacking in Chinese general population. This study aimed to investigate the association of CHG index with CKD in this specific demographic. Methods: A total of 9,095 Chinese participants aged ≥40 years were recruited from five regional communities of Luzhou city between May 2011 and December 2011. CHG index was calculated, and its possible relationships with CKD were evaluated by multivariate logistic regression analyses. Receiver operating characteristic (ROC) analysis was conducted to identify the predictive performance, and subgroup analysis evaluated its applicability in different populations. Results: The subjects with higher CHG index quartiles had significantly higher prevalence of CKD compared to those with lower quartiles ( Conclusion: The CHG index was closely associated with CKD, and might be a potential biomarker for CKD in Chinese community adults.

Indexed as

and glucose indexbiomarkerChinese populationcholesterolchronic kidney diseasecommunity adultshigh-density lipoprotein

Identifiers

PMID42199745
PMCPMC13199307

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.