Evidence map›Paper›PMID 42200975›Full record

ReviewClocks & sleep2026

Obstructive Sleep Apneas and Cardiovascular Diseases.

Vincenzo Castiglione, Paolo Morfino, Iacopo Fabiani, Francesco Gentile, Edoardo Airò, Benedetta Volpi, Daniela Cardinale, Claudio Passino, Alberto Giannoni, Michele Emdin

Abstract readReview
In one paragraph

Review in Clocks & sleep, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vincenzo CastiglioneHealth Science Interdisciplinary Research Center, Scuola Superiore Sant'Anna, 56127 Pisa, Italy.
Paolo MorfinoHealth Science Interdisciplinary Research Center, Scuola Superiore Sant'Anna, 56127 Pisa, Italy.ORCID 0000-0001-5962-9143
Iacopo FabianiHealth Science Interdisciplinary Research Center, Scuola Superiore Sant'Anna, 56127 Pisa, Italy.
Francesco GentileHealth Science Interdisciplinary Research Center, Scuola Superiore Sant'Anna, 56127 Pisa, Italy.ORCID 0000-0001-7453-3748
Edoardo AiròCardiology and Cardiovascular Medicine Division, Fondazione Monasterio, 56124 Pisa, Italy.
Benedetta VolpiCardioncology Unit, European Institute of Oncology, IRCCS, 20141 Milan, Italy.ORCID 0009-0006-0920-8176
Daniela CardinaleCardioncology Unit, European Institute of Oncology, IRCCS, 20141 Milan, Italy.ORCID 0000-0002-4038-8033
Claudio PassinoHealth Science Interdisciplinary Research Center, Scuola Superiore Sant'Anna, 56127 Pisa, Italy.
Alberto GiannoniHealth Science Interdisciplinary Research Center, Scuola Superiore Sant'Anna, 56127 Pisa, Italy.
Michele EmdinHealth Science Interdisciplinary Research Center, Scuola Superiore Sant'Anna, 56127 Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) is a sleep-disordered breathing condition characterized by recurrent upper-airway obstruction, leading to intermittent hypoxemia, sleep fragmentation, and sympathetic activation. OSA is highly prevalent in patients with cardiovascular diseases and is strongly associated with hypertension, atrial fibrillation, coronary artery disease, heart failure, and adverse prognosis. This review summarizes current evidence on the pathophysiology of OSA, its cardiovascular consequences, and available diagnostic and therapeutic strategies, with particular attention to clinical implications in cardiology practice. We discuss established treatments such as lifestyle interventions, continuous positive airway pressure, mandibular advancement devices, and selected surgical options, as well as emerging therapies, including pharmacological approaches targeting weight loss and ventilatory control. While OSA treatment improves symptoms and quality of life, evidence for cardiovascular event reduction remains heterogeneous and appears strongly influenced by patient selection and treatment adherence. Identifying patients most likely to benefit from targeted OSA management remains a key challenge.

Indexed as

continuous positive airway pressureheart failureobesityobstructive sleep apnea

Identifiers

PMID42200975
PMCPMC13214718

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.