Evidence map›Paper›PMID 42201415›Full record

Observational studySurgery today2026

Risks and outcomes of surgical site infection after minimally invasive colorectal surgery: a Japanese multicenter study.

Toshio Shiraishi, Shintaro Hashimoto, Tetsuro Tominaga, Yuma Takamura, Hiroki Katayama, Mariko Yamashita, Keisuke Noda, Shoko Tei, Rika Ono, Makoto Hisanaga and 6 more

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Toshio ShiraishiDivision of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852- 8501, Japan.
Shintaro HashimotoDivision of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852- 8501, Japan.
Tetsuro TominagaDivision of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852- 8501, Japan.
Yuma TakamuraDivision of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852- 8501, Japan.
Hiroki KatayamaDivision of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852- 8501, Japan.
Mariko YamashitaDivision of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852- 8501, Japan.
Keisuke NodaDivision of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852- 8501, Japan.
Shoko TeiDivision of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852- 8501, Japan.
Rika OnoDepartment of Surgery, Sasebo City General Hospital, 9-3 Hirasemachi, Nagasaki, 857-8511, Japan.
Makoto HisanagaDepartment of Surgery, Sasebo City General Hospital, 9-3 Hirasemachi, Nagasaki, 857-8511, Japan.
Kaido OishiDepartment of Surgery, National Hospital Organization Nagasaki Medical Center, 1-1001-1, Omura, 856-8562, Nagasaki, Japan.
Masaaki MoriyamaDepartment of Surgery, Isahaya General Hospital, 24-1, Isahaya, 854-8501, Nagasaki, Japan.
Fumitake UchidaDepartment of Surgery, Ureshino Medical Center, 4279-3 KoUreshinomachi, Shimojuku, Ureshino, Oaza, 843-0393, Saga, Japan.
Masaki KunizakiDepartment of Surgery, Saseno Chuo Hospital, 15 Yamatocho, Sasebo, 857- 1195, Japan.
Takashi NonakaDivision of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852- 8501, Japan. tnonaka@nagasaki-u.ac.jp.
Keitaro MatsumotoDivision of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852- 8501, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeStudies evaluating the occurrence, risk factors, and prognostic impact of surgical site infection (SSI) after minimally invasive surgery (MIS) for colorectal cancer are limited.

methodsThis multicenter retrospective study reviewed 3276 consecutive patients who underwent curative MIS for colorectal cancer between 2016 and 2024. Patients were divided into those who experienced incisional/deep SSI (n = 71), organ/space SSI (n = 67), and no SSI (no-SSI, n = 3138). This cohort was further subdivided into colon and rectum groups, and we examined the clinicopathological background and risk factors using a logistic regression analysis and prognosis using a Cox proportional hazards analysis.

resultsIn colon cancer, blood loss was an independent predictor of incisional/deep SSI (odds ratio (OR) 1.745, p = 0.042) and organ/space SSI (OR 6.087, 95% CI, 1.319-28.087; p = 0.020). In rectal cancer, preoperative treatment was an independent predictor of incisional/deep SSI (OR 5.619, p < 0.001) and organ/space SSI (OR 2.552, p = 0.021). In pathological node-negative patients with colon cancer, RFS (5-year RFS; 76.4% vs. 27.2% vs. 82.6%, p < 0.001) and OS (5-year OS; 80.0% vs. 56.0% vs. 86.4%, p = 0.013) were worse in the organ/space SSI group.

conclusionsPreoperative treatment and blood loss are risk factors for SSI. Even after SSI, administering appropriate adjuvant chemotherapy may be important for improving the prognosis.

Indexed as

Colorectal NeoplasmsMinimally Invasive Surgical ProceduresSurgical Wound InfectionAgedBlood Loss, SurgicalColorectal Surgical ProceduresEast Asian PeopleFemaleHumansJapanMaleMiddle AgedPrognosisRetrospective StudiesRiskRisk FactorsColorectal cancerMinimally invasive surgerySurgical site infection

Identifiers

PMID42201415

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.