Evidence mapPaperPMID 42201634Full record

ReviewProbiotics and antimicrobial proteins2026

Efficacy of Probiotics and Postbiotics in Treating Dengue Fever - A Potential Strategy to Reduce Antibody-dependent Enhancement.

Mehran Mahooti, Sajjad Ahmad, Ghazale Ahmadbeigi, Elahe Abdolalipour, Fatemeh Safaei, Kamran Mahooti, Majid Eslami, Shayan Yaghmayee, Samira Sanami, Omid Pajand

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In one paragraph

Review in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mehran MahootiDepartment of Biotechnology, Iranian Research Organization for Science and Technology, P. O. Box 3353-5111, Tehran, Iran.
Sajjad AhmadDepartment of Health and Biological Sciences, Abasyn University, Peshawar, 25000, Pakistan.
Ghazale AhmadbeigiDepartment of Biotechnology, Faculty of Advanced Medical Sciences, Tehran Medical Branch, Islamic Azad University, Tehran, Iran.
Elahe AbdolalipourDepartment of Virology, Pasteur Institute of Iran, P.O.Box: 1316943551, Tehran, Iran.
Fatemeh SafaeiDepartment of Biotechnology, Iranian Research Organization for Science and Technology, P. O. Box 3353-5111, Tehran, Iran.
Kamran MahootiDepartment of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran.
Majid EslamiResearch Center of Physiology, Semnan University of Medical Sciences, Semnan, Iran.
Shayan YaghmayeeResearch Center of Physiology, Semnan University of Medical Sciences, Semnan, Iran.
Samira SanamiResearch Center of Physiology, Semnan University of Medical Sciences, Semnan, Iran. samirasanami34@yahoo.com.
Omid PajandSocial Determinants of Health Research Center, Semnan University of Medical Sciences, Semnan, Iran. om24pa@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue virus (DENV), a member of the flavivirus family, is transmitted by the Aedes mosquito, with an incubation period of typically four to ten days, and causes a clinical spectrum of Dengue virus infection (DVI), ranging from classic dengue fever (DF) to sever illness, with symptoms such as vascular leakage, hemorrhage, organ dysfunction, and dysregulated inflammatory responses mediated by cytokines such as interleukin 6 (IL-6). However, Concerns about the absence of effective antiviral treatments or the efficacy and safety limitations of existing vaccines have led to considering novel treatment ways. Probiotics and postbiotics modulate mucosal and systemic immunity in a variety of ways, including mechanisms such as interaction with intestinal epithelial cells and dendritic cells (DCs), increased antigen (Ag) presentation, modulation of the toll-like receptor (TLR) signaling pathway, upregulation of regulatory pathways, and stimulation of antiviral cellular responses, including increased interferon-gamma (IFN-γ) production and cluster of differentiation 4

Indexed as

DENVDVIIFN-γPostbioticProbiotic

Identifiers

PMID42201634

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.