Evidence map›Paper›PMID 42201784›Full record

ArticleActa crystallographica. Section D, Structural biology2026

Photoisomerization detected in a fully wavelength-tunable rhodopsin mimic system.

Nona Ehyaei, Courtney Bingham, Katelyn Silva, Zahra Nossoni, Hadi Nayebi Gavgani, Meisam Nosrati, Joelle Eaves, Mustapha Akhdar, Chrysoula Vasileiou, Babak Borhan and 1 more

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In one paragraph

Article in Acta crystallographica. Section D, Structural biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nona EhyaeiDepartment of Chemistry, Michigan State University, East Lansing, MI 48824, USA.
Courtney BinghamDepartment of Chemistry, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0001-5920-5543
Katelyn SilvaDepartment of Chemistry, Michigan State University, East Lansing, MI 48824, USA.
Zahra NossoniDepartment of Chemistry, Michigan State University, East Lansing, MI 48824, USA.
Hadi Nayebi GavganiDepartment of Chemistry, Michigan State University, East Lansing, MI 48824, USA.
Meisam NosratiDepartment of Chemistry, Michigan State University, East Lansing, MI 48824, USA.
Joelle EavesDepartment of Chemistry, Michigan State University, East Lansing, MI 48824, USA.
Mustapha AkhdarDepartment of Chemistry, Michigan State University, East Lansing, MI 48824, USA.
Chrysoula VasileiouDepartment of Chemistry, Michigan State University, East Lansing, MI 48824, USA.
Babak BorhanDepartment of Chemistry, Michigan State University, East Lansing, MI 48824, USA.
James H GeigerDepartment of Chemistry, Michigan State University, East Lansing, MI 48824, USA.

Funding

Protein/Chromphore Interactions via Protein Design: Interrogation and ApplicationR01GM101353 · NIGMS · MICHIGAN STATE UNIVERSITY · PI BORHAN, BABAK, GEIGER, JAMES H · 2013 to 2022
$2.6M
National Institutes of Health, National Institute of General Medical Sciences R01GM101353NIGMS NIH HHS R01 GM101353
6 · The paper itself

Abstract

We describe the photoisomerization of the retinylidene protonated Schiff base in human retinol-binding protein II (hCRBPII) and the role of water molecules in this process. We characterize the photoisomerization of the 15-cis/all-trans retinylidene protonated Schiff base in this system using UV-visible spectroscopy and atomic-resolution X-ray crystallography. We further demonstrate a process where the pK

Indexed as

RhodopsinCrystallography, X-RayHumansIsomerismLightModels, MolecularProtein ConformationSchiff BasesRhodopsinSchiff Basesbacteriorhodopsinprotein designprotein electrostaticsrhodopsin mimicsingle-crystal photolysis

Identifiers

PMID42201784
PMCPMC13224928

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.