Evidence map›Paper›PMID 42204303›Full record

Trial reportScientific reports2026

Evaluation of the impact of Comprehensive Medication Management on health outcomes in people living with hypertension: a pragmatic clinical trial.

Taiana de Alencar, Maria Paula Debona Vieira, Mayra Cardozo Mendes, Elisabeth Maria López De Prado, Emilly Velasquez Nicolini, Andressa Carlos Barbosa, Bárbara Brambila-Manso, Maria Eduarda Silva Pinto, Larissa Couto-Rosa, Alfredo Dias de Oliveira-Filho and 3 more

Abstract readPragmatic Clinical TrialRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Taiana de AlencarResearch Group on Implementation and Integration of Clinical Pharmacy Services in Brazilian Health System (SUS), Department of Pharmacy and Nutrition, Federal University of Espírito Santo, Alto Universitario, S/N - Guararema, Alegre, Espírito Santo, Brazil.
Maria Paula Debona VieiraResearch Group on Implementation and Integration of Clinical Pharmacy Services in Brazilian Health System (SUS), Department of Pharmacy and Nutrition, Federal University of Espírito Santo, Alto Universitario, S/N - Guararema, Alegre, Espírito Santo, Brazil.
Mayra Cardozo MendesResearch Group on Implementation and Integration of Clinical Pharmacy Services in Brazilian Health System (SUS), Department of Pharmacy and Nutrition, Federal University of Espírito Santo, Alto Universitario, S/N - Guararema, Alegre, Espírito Santo, Brazil.
Elisabeth Maria López De PradoResearch Group on Implementation and Integration of Clinical Pharmacy Services in Brazilian Health System (SUS), Department of Pharmacy and Nutrition, Federal University of Espírito Santo, Alto Universitario, S/N - Guararema, Alegre, Espírito Santo, Brazil.
Emilly Velasquez NicoliniResearch Group on Implementation and Integration of Clinical Pharmacy Services in Brazilian Health System (SUS), Department of Pharmacy and Nutrition, Federal University of Espírito Santo, Alto Universitario, S/N - Guararema, Alegre, Espírito Santo, Brazil.
Andressa Carlos BarbosaResearch Group on Implementation and Integration of Clinical Pharmacy Services in Brazilian Health System (SUS), Department of Pharmacy and Nutrition, Federal University of Espírito Santo, Alto Universitario, S/N - Guararema, Alegre, Espírito Santo, Brazil.
Bárbara Brambila-MansoResearch Group on Implementation and Integration of Clinical Pharmacy Services in Brazilian Health System (SUS), Department of Pharmacy and Nutrition, Federal University of Espírito Santo, Alto Universitario, S/N - Guararema, Alegre, Espírito Santo, Brazil.
Maria Eduarda Silva PintoResearch Group on Implementation and Integration of Clinical Pharmacy Services in Brazilian Health System (SUS), Department of Pharmacy and Nutrition, Federal University of Espírito Santo, Alto Universitario, S/N - Guararema, Alegre, Espírito Santo, Brazil.
Larissa Couto-RosaResearch Group on Implementation and Integration of Clinical Pharmacy Services in Brazilian Health System (SUS), Department of Pharmaceutical Sciences, Federal University of Espírito Santo, Av. Mal. Campos, 1468 - Maruípe, Vitória, Espírito Santo, Brazil. larissacoutorosa@hotmail.com.
Alfredo Dias de Oliveira-FilhoDepartment of Pharmacy, Federal University of Sergipe, Cidade Univ. Prof. José Aloísio de Campos, Av. Marcelo Deda Chagas, S/N, Rosa Elze, São Cristóvão, Sergipe, Brazil.
Dyego Carlos AraújoLaboratory for Innovation in Health Care, Department of Pharmaceutical Sciences, Federal University of Espírito Santo, Av. Mal. Campos, 1468 - Maruípe, Vitória, Espírito Santo, Brazil.
Kérilin Stancine Santos RochaLaboratory for Innovation in Health Care, Department of Pharmaceutical Sciences, Federal University of Espírito Santo, Av. Mal. Campos, 1468 - Maruípe, Vitória, Espírito Santo, Brazil.
Genival Araujo Dos Santos-JúniorResearch Group on Implementation and Integration of Clinical Pharmacy Services in Brazilian Health System (SUS), Department of Pharmacy and Nutrition, Federal University of Espírito Santo, Alto Universitario, S/N - Guararema, Alegre, Espírito Santo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension is a chronic condition frequently requiring long-term pharmacotherapy, which may increase the risk of medication-related problems. Comprehensive Medication Management (CMM) has been associated with improvements in health outcomes in patients with hypertension; however, evidence from pragmatic randomized clinical trials in primary care settings remains limited. This study aimed to evaluate the association between pharmacist-led CMM on clinical, anthropometric, humanistic, and cardiovascular risk outcomes among patients with hypertension treated within the public health care network of Alegre, Espírito Santo, Brazil. A pragmatic, single-blind, randomized controlled clinical trial with a 12-month follow-up was conducted. A total of 128 adults with hypertension were randomized in a 1:1 ratio to the intervention group (CMM) or the control group (usual care). No statistically significant between-group differences were observed for clinical, anthropometric, or humanistic parameters; cardiovascular risk was the only outcome showing a statistically significant time × group interaction (p = 0.039; η

Indexed as

Antihypertensive AgentsHypertensionAgedBlood PressureBrazilFemaleHumansMaleMiddle AgedPharmacistsQuality of LifeSingle-Blind MethodTreatment OutcomeAntihypertensive AgentsClinical TrialHypertensionPharmacistsPharmacy practice

Identifiers

PMID42204303
PMCPMC13443747

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.