Evidence mapPaperPMID 42204621Full record

ReviewJournal of medical case reports2026

Successful treatment with plasmapheresis of severe hypertriglyceridemic acute pancreatitis complicated by fat overload syndrome caused by lipid injectable emulsion: a case report and review of the literature.

Dou-Dou Li, Kai Liu, Ba Yi Liu, Hua Min Wang, Bing Lin, Hao Yang, Bao-Ping Xu

Abstract readCase ReportsReview
In one paragraph

Review in Journal of medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dou-Dou Li *Department of Intensive Care Unit, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, No. 3, Xinkang Road, Xiqu District, Guangzhou, Zhongshan, 528400, China.
Kai Liu *Anhui University of Traditional Chinese Medicine, Hefei, 230031, Anhui, China.
Ba Yi LiuDepartment of Intensive Care Unit, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, No. 3, Xinkang Road, Xiqu District, Guangzhou, Zhongshan, 528400, China.
Hua Min WangDepartment of Intensive Care Unit, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, No. 3, Xinkang Road, Xiqu District, Guangzhou, Zhongshan, 528400, China.
Bing LinDepartment of Intensive Care Unit, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, No. 3, Xinkang Road, Xiqu District, Guangzhou, Zhongshan, 528400, China.
Hao YangDepartment of ICU, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 5, Haiyuncang, Dongcheng District, Beijing, 100000, China. 819494817@qq.com.
Bao-Ping XuDepartment of Intensive Care Unit, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine, No. 3, Xinkang Road, Xiqu District, Guangzhou, Zhongshan, 528400, China. xu131406@qq.com.

Funding

Fundamental Research Funds for the Central Universities of Beijing University of Chemical Technology 2025-BUCMXJKY-060The High-Level Scientific Research Project of Dongzhimen Hospital, Beijing University of Chinese Medicine No. DZMG-QNZX-24008
6 · The paper itself

Abstract

backgroundHypertriglyceridemic acute pancreatitis (HTG-AP) and fat overload syndrome caused by lipid injectable emulsion (ILE) are rare in clinical practice. Although the treatment of HTG-AP with plasmapheresis has previously been reported, only a few reports describe the application of plasmapheresis to treat HTG-AP and fat overload syndrome caused by ILE. CASE PRESENTATION: We report a case diagnosed with severe HTG-AP and fat overload syndrome, based on laboratory findings and abdominal computed tomography, caused by intravenous infusion of ILE for about 3 weeks without monitoring of serum triglyceride (TG) levels in a 78-year-old Chinese female patient with a history of esophageal cancer. Conventional treatments were attempted; however, the patient progressively developed worsening abdominal pain and notably elevated inflammatory biomarkers, including C-reactive protein and procalcitonin levels. Plasmapheresis treatment was performed immediately to lower serum TG levels and prevent the complication of acute pancreatitis (AP) due to hypertriglyceridemia. After two consecutive plasmapheresis sessions, the patient's TG and total cholesterol levels remarkably decreased to 13.57 and 8.62 mmol/L, respectively. She also showed considerable improvement in her abdominal symptoms.

conclusionHTG-AP and fat overload syndrome can be associated with intravenous infusion of ILE. Monitoring serum TG levels while utilizing ILE is necessary. Plasmapheresis should be considered an effective treatment measure for severe HTG-AP or fat overload syndrome caused by ILE, because it rapidly lowers serum TG levels and may prevent to be useful in ameliorating the course of acute pancreatitis.

Indexed as

Fat Emulsions, IntravenousHypertriglyceridemiaPancreatitisPlasmapheresisAcute DiseaseAgedFemaleHumansTomography, X-Ray ComputedTreatment OutcomeTriglyceridesFat Emulsions, IntravenousTriglyceridesAdverse drug reactionCase reportFat overload syndromeHypertriglyceridemia acute pancreatitisLipid injectable emulsionParenteral nutritionPlasmapheresis

Identifiers

PMID42204621
PMCPMC13393881

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.