ArticleNutrition journal2026
Seafood consumption and incident diabetes mellitus in middle-aged and elderly Chinese: results from the 4 C study.
Article in Nutrition journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
45 authors.
Funding
Abstract
backgroundThere is an urgent need to implement population-based actions to prevent diabetes mellitus (DM) in China. However, the current knowledge is limited on a prospective association of seafood intake with DM risk in Chinese adults. We aimed to determine the association between seafood consumption and the incident DM in a nationwide cohort of Chinese populations.
methodsA prospective cohort study of 104,816 participants, free of DM, aged ≥ 40 years across various geographical regions in China was conducted at baseline (China Cardiometabolic Disease and Cancer study). Habitual consumptions of seafood were assessed using a semi-quantitative food frequency questionnaire, and DM was diagnosed according to the WHO 1999 criteria. Primary outcomes were the incident DM, presented as hazard rations (HRs) with 95% confidence intervals (CIs) that were examined with Cox proportional model with adjustments for relevant covariates across quartiles of seafood consumptions, with the lowest quartile as the reference. Dose-response analyses were evaluated using the restricted cubic spline regression with tests for nonlinearity.
resultsDuring the mean follow-up period of 3.60 years, 7,105 incident DM cases were present among the 104,816 participants. Participants at the highest quartile of seafood-consumption amount had a lower risk of DM than those at the lowest (HR: 0.87, 95% CI: 0.80-0.94). There is a steep decrease in the risk of DM with the increasing consumption of seafood within the cumulative amount of 200.00 g/week, which further strengthened gradually thereafter (P for nonlinearity < 0.001).
conclusionsIn the middle-aged, elderly Chinese population, higher seafood consumption was nonlinearly associated with a lower risk of incident DM, and the cutoff amount of 200.00 g/week was appropriate.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.