Evidence map›Paper›PMID 42205278›Full record

ArticleRSC advances2026

Development of new quinoline-triazole based hybrids: synthesis, nano-encapsulation, DFT calculations, and evaluation of antidiabetic and antioxidant activity.

Fatma M Elhalmoushy, Mohamed N Abd Al Moaty, Alaa S Hegazy, Saied M Soliman, Mazen Sherif, Doaa A Ghareeb, Mohamed Hagar, Manar Ahmed Fouad

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fatma M ElhalmoushyDepartment of Chemistry, Faculty of Science, Alexandria University P.O. Box 426 Alexandria 21321 Egypt mohamed.hagar@alexu.edu.eg manar.ahmed@alexu.edu.eg.ORCID https://orcid.org/0009-0004-2426-9546
Mohamed N Abd Al MoatyDepartment of Chemistry, Faculty of Science, Alexandria University P.O. Box 426 Alexandria 21321 Egypt mohamed.hagar@alexu.edu.eg manar.ahmed@alexu.edu.eg.ORCID https://orcid.org/0000-0003-2843-9704
Alaa S HegazyDepartment of Medical Laboratory Technology, Faculty of Applied Health Sciences Technology, Pharos University in Alexandria Alexandria Egypt.ORCID https://orcid.org/0000-0002-6904-3880
Saied M SolimanDepartment of Chemistry, Faculty of Science, Alexandria University P.O. Box 426 Alexandria 21321 Egypt mohamed.hagar@alexu.edu.eg manar.ahmed@alexu.edu.eg.ORCID https://orcid.org/0000-0001-8405-8370
Mazen SherifBio-screening and Preclinical Trial Lab, Biochemistry Department, Faculty of Science, Alexandria University Alexandria Egypt.
Doaa A GhareebBio-screening and Preclinical Trial Lab, Biochemistry Department, Faculty of Science, Alexandria University Alexandria Egypt.ORCID https://orcid.org/0000-0003-3327-4377
Mohamed HagarDepartment of Chemistry, Faculty of Science, Alexandria University P.O. Box 426 Alexandria 21321 Egypt mohamed.hagar@alexu.edu.eg manar.ahmed@alexu.edu.eg.ORCID https://orcid.org/0000-0003-0169-7738
Manar Ahmed FouadDepartment of Chemistry, Faculty of Science, Alexandria University P.O. Box 426 Alexandria 21321 Egypt mohamed.hagar@alexu.edu.eg manar.ahmed@alexu.edu.eg.ORCID https://orcid.org/0000-0001-9128-9118

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, the development of effective and safe antidiabetic drugs remains a major challenge in diabetes management. This study reports the design and synthesis of new quinoline-based hybrids, featuring an oxymethylene-linked 1,2,3-triazole core and integrated 1,2,4-triazole pharmacophores, alongside their chitosan-encapsulated derivatives, as prospective multitarget antidiabetic agents. The synthesized compounds were evaluated for their

Identifiers

PMID42205278
PMCPMC13202433

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.