ReviewJournal of inflammation research2026
The Pathogenesis and Therapies of Acute Pancreatitis: A Bibliometric Analysis from 2003 to 2025.
Review in Journal of inflammation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Acute pancreatitis (AP) is an inflammatory disorder with rising global incidence. Substantial progress in elucidating AP pathophysiology has been achieved over the past two decades. This study aims to assess the evolution of AP pathogenesis and therapies through quantitative methodologies. Methods: Basic research articles addressing AP pathogenesis and therapies published between 2003 and 2025 were retrieved from the Web of Science database. Bibliometric visualization was performed with VOSviewer and CiteSpace, and statistical graphics with GraphPad Prism. Results: Among 632 publications, China led in output, while the USA had the highest impact. Shanghai Jiao Tong University and Markus M. Lerch were the most productive institution and author, respectively. Pancreas was the leading journal. Keyword analysis revealed key mechanistic themes including "oxidative stress", "nf-kappa-b", and "trypsinogen activation", alongside emerging research foci such as "gut microbiota" and "autophagy". Rodents were the primary models, with cerulein as the common inducer. Recent hotspots include acinar cell ferroptosis and pyroptosis, alongside pivotal immune themes of neutrophil extracellular traps, macrophage polarization, and Treg/Th17 balance. Innovative therapies encompassed gut microbiota modulation, nanotherapy, and traditional Chinese medicine. Conclusion: This investigation provides methodological references for establishing AP experimental models, and delineates promising future investigative trajectories.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.