Evidence mapPaperPMID 42209294Full record

ArticleDiabetes, obesity & metabolism2026

Association of Physical Activity With All-Cause and CVD Mortality Across Metabolic and Obesity Phenotypes.

Yunmin Han, Younghwan Choi, Soomin Lee, Yeon Soo Kim

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Article in Diabetes, obesity & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yunmin HanDepartment of Physical Education, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-9453-4692
Younghwan ChoiDepartment of Physical Education, Seoul National University, Seoul, Republic of Korea.
Soomin LeeDepartment of Physical Education, Seoul National University, Seoul, Republic of Korea.
Yeon Soo KimDepartment of Physical Education, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-1447-0196

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo examine the independent and joint associations of metabolic status, obesity, and physical activity with all-cause and cardiovascular disease (CVD) mortality across metabolic-obesity phenotypes. MATERIALS AND

methodsWe analysed 442 666 adults from the Korean National Health Insurance Service health screening cohort (2009-2012). Metabolic status was defined using modified NCEP-ATP III criteria (elevated triglycerides, low HDL-C, elevated blood pressure or antihypertensive use, and elevated fasting glucose or antidiabetic use); ≥ 2 abnormalities indicated metabolically unhealthy. Obesity was defined as BMI ≥ 25 kg/m

resultsIn the primary multivariable model (Model 2a), compared with MHL, MUHL had the highest all-cause mortality (HR 1.23, 95% CI 1.19-1.26), whereas MUHO was not significantly associated with all-cause mortality (HR 0.97, 95% CI 0.94-1.01), and MHO showed lower risk (HR 0.85, 95% CI 0.81-0.89). Higher physical activity was consistently associated with lower all-cause and CVD mortality in a dose-response manner, and joint analyses showed progressively lower mortality across all metabolic-obesity phenotypes with increasing activity levels.

conclusionsMetabolic-obesity phenotypes were associated with differential mortality risk, and higher physical activity was associated with lower all-cause and CVD mortality across phenotypes.

Indexed as

Cardiovascular DiseasesExerciseMetabolic SyndromeObesityAdultBody Mass IndexCause of DeathFemaleHumansMaleMiddle AgedObesity, Metabolically BenignPhenotypeRepublic of Koreaall‐cause mortalitycardiovascular disease mortalitycohort studymetabolic–obesity phenotypesphysical activity

Identifiers

PMID42209294
PMCPMC13341358

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.