Evidence map›Paper›PMID 42209727›Full record

ArticleMikrochimica acta2026

Hemoglobin-assisted, ZIF-derived porous bimetallic FeCo/N-C nanozyme with high oxidase-like activity for colorimetric sensing.

Zhenzhen Wang, Yiyu Chen, Xuexia Lin, Huiting Lian, Bin Liu, Xiaofeng Wei

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zhenzhen WangCollege of Materials Science and Engineering, Huaqiao University, Xiamen, 361021, China.
Yiyu ChenCollege of Materials Science and Engineering, Huaqiao University, Xiamen, 361021, China.
Xuexia LinCollege of Materials Science and Engineering, Huaqiao University, Xiamen, 361021, China.
Huiting LianCollege of Materials Science and Engineering, Huaqiao University, Xiamen, 361021, China.
Bin LiuCollege of Materials Science and Engineering, Huaqiao University, Xiamen, 361021, China. bliu@hqu.edu.cn.
Xiaofeng WeiCollege of Materials Science and Engineering, Huaqiao University, Xiamen, 361021, China. xfwei@hqu.edu.cn.

Funding

National Natural Science Foundation of China 21575044National Natural Science Foundation of China 21904043Natural Science Foundation of Fujian Province of China 2024J01085Natural Science Foundation of Xiamen, China 3502Z202472051
6 · The paper itself

Abstract

Oxidative stress caused by excessive reactive oxygen species (ROS) is related to many diseases, and the importance of accurate detection of antioxidants is emphasized. Ascorbic acid (AA), a representative antioxidant, is widely used to assess total antioxidant capacity. Herein, we report the rational design of a bimetallic FeCo/N-C nanozyme via pyrolysis of a hemoglobin (Hb)-doped ZIF-67@ZIF-8 precursor. The Hb precursor plays a dual role: it acts as a molecular porogen to produce hierarchical porous structure, and as a coordination modulator to facilitate the formation of highly dispersed metal sites, thereby preventing cobalt aggregation and enhancing mass transfer. Crucially, the synthesized FeCo/N-C nanozyme exhibits exceptional oxidase-like activity by catalyzing the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) via a singlet oxygen (¹O

Indexed as

Ascorbic AcidCobaltColorimetryHemoglobinsMetal-Organic FrameworksNanostructuresBenzidinesCatalysisHumansImidazolesLimit of DetectionOxidation-ReductionOxidoreductasesPorosity3,3',5,5'-tetramethylbenzidineAscorbic AcidBenzidinesCobaltHemoglobinsImidazolesMetal-Organic FrameworksOxidoreductasesAscorbic acidColorimetric sensorFeCo/N-CNanozymeOxidase-like activity

Identifiers

PMID42209727

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.