Evidence map›Paper›PMID 42209746›Full record

SynthesisNature human behaviour2026

A systematic overview and second-order meta-analysis of nature-based interventions for stress, anxiety and depression.

Esmaeel Saeedy Robat, Mohammad Hossein Bayazi, Mahdi Nayyeri, Ali Asghar Yasaghi, Saeed Taimory

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Nature human behaviour, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Esmaeel Saeedy RobatDepartment of Psychology, Tay.C., Islamic Azad University, Taybad, Iran. es.saeedy@iau.ac.ir.ORCID http://orcid.org/0000-0001-9899-8523
Mohammad Hossein BayaziDepartment of Psychology, ToJ.C., Islamic Azad University, Torbat Jam, Iran.
Mahdi NayyeriDepartment of Psychology, ToJ.C., Islamic Azad University, Torbat Jam, Iran.
Ali Asghar YasaghiDepartment of Psychology, Ma.C., Islamic Azad University, Mashhad, Iran.
Saeed TaimoryDepartment of Psychology, ToJ.C., Islamic Azad University, Torbat Jam, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of stress, anxiety and depression is increasing globally. Nature-based interventions (NBIs), using natural settings to promote well-being, are recognized for their potential benefits, but synthesis is lacking. We conducted a preregistered (PROSPERO: CRD42024577017) systematic overview and second-order meta-analysis encompassing 116 systematic reviews in the overview and 30 reviews in the second-order meta-analysis from ten databases (representing 3,870 primary studies, over ten million estimated participants). The included systematic reviews evaluated NBI effects against diverse control conditions. Review quality was assessed (AMSTAR 2) alongside potential publication bias. NBIs were effective in reducing overall negative outcomes compared with controls (standardized mean difference (SMD), -0.69; 95% CI, -1.05 to -0.33), with significant reductions observed specifically for anxiety (SMD = -0.83; 95% CI, -1.19 to -0.47), depressive symptoms (SMD = -0.72; 95% CI, -1.05 to -0.40), heart rate (SMD = -0.70; 95% CI, -1.17 to -0.23) and negative affect (SMD = -0.61; 95% CI, -1.06 to -0.16). NBIs also enhanced positive outcomes (SMD = 0.90; 95% CI, 0.33 to 1.46), particularly positive affect (SMD = 0.52; 95% CI, 0.28 to 0.75) and relaxation (SMD = 2.85; 95% CI, 1.86 to 3.84). For positive outcomes, the SMD for psychological dimensions was 1.18 (95% CI, 0.66 to 1.69), while the SMD for physiological dimensions was 0.24 (95% CI, -0.19 to 0.67). The predominance of passive control groups and inconsistent intervention definitions across primary studies limit conclusions on relative efficacy. The findings confirm NBI benefits but highlight the need for high-quality primary studies with active comparators to maximize intervention benefits.

Indexed as

AnxietyDepressionStress, PsychologicalHumans

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.