Evidence map›Paper›PMID 42210294›Full record

ArticleThe New phytologist2026

Kinetic parameter prediction using neural networks identifies limitations to C

Philipp Wendering, John Ferguson, Rudan Xu, Johannes Kromdijk, Zoran Nikoloski

Abstract read
In one paragraph

Article in The New phytologist, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philipp WenderingDepartment of Plant Science, University of Cambridge, Downing Street, Cambridge, CB2 3EA, UK.ORCID https://orcid.org/0000-0002-0155-6217
John FergusonSchool of Life Sciences, University of Essex, Colchester, CO4 3SQ, UK.ORCID https://orcid.org/0000-0003-3603-9997
Rudan XuBioinformatics, Institute of Biochemistry and Biology, University of Potsdam, Karl-Liebknecht-Str. 24-25, Potsdam, 14476, Germany.ORCID https://orcid.org/0000-0002-4980-1453
Johannes KromdijkDepartment of Plant Science, University of Cambridge, Downing Street, Cambridge, CB2 3EA, UK.ORCID https://orcid.org/0000-0003-4423-4100
Zoran NikoloskiBioinformatics, Institute of Biochemistry and Biology, University of Potsdam, Karl-Liebknecht-Str. 24-25, Potsdam, 14476, Germany.ORCID https://orcid.org/0000-0003-2671-6763

Funding

Biotechnology and Biological Sciences Research Council BB/Y51388X/1
6 · The paper itself

Abstract

Kinetic models of photosynthesis enable time-resolved predictions of traits related to this key process and provide the means to identify factors limiting photosynthesis. However, the use of large-scale models is currently limited by the lack of efficient approaches to estimate the hundreds of genotype-specific kinetic parameters. Here, we present C4TUNE, an artificial neural network that can efficiently predict parameters of a large-scale photosynthesis model from photosynthesis response curves. C4TUNE was trained on a biologically relevant synthetic dataset comprising matched samples of parameters and response curves obtained using a C

Indexed as

CarbonNeural Networks, ComputerPhotosynthesisZea maysComputer SimulationGenotypeKineticsModels, BiologicalCarbonC4 photosynthesisdeep learninggas exchangekinetic modelparameterization

Identifiers

PMID42210294
PMCPMC13326549

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.