ArticleBrain, behavior, & immunity - health2026
Associations among discrimination, genetic susceptibility to inflammation, and C-reactive protein.
Article in Brain, behavior, & immunity - health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
Genetic liability to inflammation may lead to heightened perception of discrimination (gene-environment correlation) or interact with discrimination exposure to amplify inflammation risk (gene-environment interaction). The present study examined the interrelationship between genetic predisposition, self-reported discrimination exposure, and inflammatory phenotypes. Data came from 6344 participants in the 2016 Health and Retirement Study Venous Blood Study. Polygenic risk scores for high-sensitivity C-reactive protein (PRS-hsCRP) were derived from genome-wide association study summary statistics. Daily discrimination was assessed using the Everyday Discrimination Scale and hsCRP was quantified from serum and natural log-transformed for analysis. Linear regression models were fit using multiple imputation, and analyses were stratified by ethnicity. Perceived discrimination exposure was positively associated with ln(hsCRP) levels among European American (b = 0.06, 95% CI: 0.02 to 0.10,
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