ArticleFrontiers in nutrition2026
MIND diet moderates the associations between cerebrovascular and neurodegenerative disease burden and cognition.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Relationship Between Cognitive Performance and Anthropometric Status, Dietary Diversity, and Diet Quality in Older Turkish Adults: A Cross-Sectional Study.Journal of clinical medicine · 2026Article
- A network analysis of dietary patterns, social participation patterns, and cognitive function in Chinese older adults.Frontiers in psychiatry · 2026Article
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Authors and funding
13 authors.
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Abstract
Introduction: The Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet is associated with reduced dementia risk, but its role in moderating pathology-cognition relationships in high-risk populations remains unclear. This study examined associations of the MIND diet and Healthy Eating Index (HEI) with cognition and tested whether diet quality modifies the impact of brain pathology on cognitive performance. Methods: Sixty-six older adults (aged 60-82 years; mean education of 12 years, 65% Black, 73% female) completed MRI and the VioScreen food frequency questionnaire (FFQ). Multivariable linear regression models examined associations between diet scores (MIND, HEI-2020) and cognitive outcomes (cognition composite, memory, executive function), adjusting for age, sex, and education level. Interaction analyses cross-sectionally tested whether diet moderated relationships between structural brain pathology-white matter hyperintensity (WMH), hippocampal, and cortical volumes-and cognition, followed by Results: Higher MIND diet scores were independently associated with better memory performance ( Conclusion: The MIND diet may buffer the cognitive consequences of cerebrovascular pathology and cortical atrophy in older adults at elevated dementia risk and promote cognitive resilience over general healthy eating guidelines.
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