Evidence map›Paper›PMID 42211249›Full record

ReviewInternational journal of cardiology. Heart & vasculature2026

Hemodynamics in heart: the critical role of hemodynamics in myocardial tissue development and regenerative remodeling.

Ruiying Zhang, Xingyi Sun, Yijia Liu, Yiran Meng, Yue Zheng, Chunmei Zhang, Shuo Wang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of cardiology. Heart & vasculature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ruiying ZhangTianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Xingyi SunTianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Yijia LiuDepartment of Cardiology, Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300151, China.
Yiran MengTianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Yue ZhengState Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Chunmei ZhangTianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Shuo WangTianjin University of Traditional Chinese Medicine, Tianjin 301617, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemodynamic factors are essential in influencing cellular behaviors and facilitating the restoration of tissue structure and function through mechanotransduction pathways. This review explores the pivotal role of hemodynamics in the development of myocardial tissue and the remodeling processes involved in tissue regeneration. We systematically analyze the regulatory effects of hemodynamic conditions during embryonic heart development, adult cardiac regeneration, and pathological remodeling processes. The review summarizes the latest research findings and potential therapeutic strategies aimed at harnessing hemodynamic influences for the treatment of cardiovascular diseases. By shedding light on these mechanisms, we aim to provide a theoretical foundation to inform future therapeutic approaches in cardiovascular medicine.

Indexed as

Cardiac remodellingHemodynamicsMechanotransductionMyocardial developmentTherapeutic strategiesTissue regeneration

Identifiers

PMID42211249
PMCPMC13213733

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.