Evidence map›Paper›PMID 42211436›Full record

ReviewFrontiers in allergy2026

A meta-analysis of acupuncture at the sphenopalatine ganglion for the treatment of allergic rhinitis.

Qiang Liu, Weiying Zhu, YongDong Sun, Long Chen

Abstract readReview
In one paragraph

Review in Frontiers in allergy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qiang LiuDepartment of Otolaryngology Head and Neck Surgery, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Weiying ZhuDepartment of Otolaryngology Head and Neck Surgery, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, China.
YongDong SunDepartment of Otolaryngology Head and Neck Surgery, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Long ChenDepartment of Otolaryngology Head and Neck Surgery, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Allergic rhinitis (AR) imposes a significant global health burden. While conventional treatments include medications and immunotherapy, acupuncture at the sphenopalatine ganglion (SPG) has emerged as a promising alternative. This meta-analysis evaluates the efficacy of SPG acupuncture for AR. Methods: We searched CNKI, PubMed, Web of Science, SinMed, and Cochrane Library (inception to May 2024) for RCTs comparing SPG acupuncture against controls (conventional acupuncture/sham/medications). Primary outcomes were Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) change, Total Nasal Symptom Score (TNSS) change, and total effective rate. Risk of bias was assessed using Cochrane criteria. Meta-analyses used random/fixed models in RevMan 5.3; evidence quality was graded via GRADE. Results: Eleven RCTs (= 732) were analyzed. SPG acupuncture significantly: Improved RQLQ (MD = 7.63, 95% CI: 2.81 to 12.45, Conclusion: Eleven RCTs with a total of 732 participants were analyzed. SPG acupuncture improves quality of life, nasal symptoms, and clinical efficacy in AR patients vs. conventional treatments, though evidence quality remains low to moderate. It represents a viable adjunct therapy, warranting further high-quality trials. SYSTEMATIC REVIEW REGISTRATION: https://www.crd.york.ac.uk/prospero/.

Indexed as

allergic rhinitisoverall response rateRQLQsphenopalatine ganglionsystematic review and meta-analysisTNSS

Identifiers

PMID42211436
PMCPMC13212333

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.