Evidence map›Paper›PMID 42212055›Full record

ArticleInfection and drug resistance2026

Hyperbaric Oxygen Treatment as a Novel Add-on in Selected Patients with Infective Endocarditis - A Safety and Feasibility Trial.

Mia Marie Pries-Heje, Christian Johann Lerche, Emil Fosbøl, Martin Forchhammer, Rasmus Bo Hasselbalch, Franziska Schwartz, Anne Sofie L Siebert, Peter Østrup Jensen, Henrik Rottensten, Kasper Iversen and 3 more

Abstract read
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In one paragraph

Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mia Marie Pries-HejeDepartment of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.ORCID 0000-0002-9407-5112
Christian Johann LercheDepartment of Clinical Microbiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Emil FosbølDepartment of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Martin ForchhammerDepartment of Anaesthesiology, Centre of Head and Orthopedics, Rigshospitalet, Copenhagen University, Copenhagen, Denmark.
Rasmus Bo HasselbalchDepartment of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Franziska SchwartzDepartment of Clinical Microbiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Anne Sofie L SiebertDepartment of Clinical Microbiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Peter Østrup JensenDepartment of Clinical Microbiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.ORCID 0000-0003-1648-7186
Henrik RottenstenDepartment of Anaesthesiology, Centre of Head and Orthopedics, Rigshospitalet, Copenhagen University, Copenhagen, Denmark.
Kasper IversenDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-0504-8487
Henning BundgaardDepartment of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Ole HyldegaardDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-1147-379X
Claus MoserDepartment of Clinical Microbiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Infective endocarditis (IE) is associated with a high morbidity and mortality. Adjunctive hyperbaric oxygen (HBO Methods: This Phase I/II feasibility and safety trial included patients aged >18 years, with left-sided IE caused by Gram-positive cocci. The intervention consisted of six consecutive HBO Results: Of 26 screened patients, 13 patients were included and 10 (77%) completed the HBO Conclusion: Adjunctive HBO Study Id: EudraCT (2019-000857-29). Danish Medicines Agency (2019030362).

Indexed as

adjunctive therapybiofilm infectionhyperbaric oxygeninfective endocarditis

Identifiers

PMID42212055
PMCPMC13212165

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.