Evidence map›Paper›PMID 42212759›Full record

ArticleJournal of studies on alcohol and drugs2026

Characteristics of People Who Inject Drugs Approached for Injection Assistance in Rural Kentucky.

April Young, Ryli Hockensmith, Preston T Tolbert, Susan Westneat, Peter Vickerman, Jack Stone, Hilary L Surratt, Kayo Fujimoto, Hannah K Knudsen, Rachel Vickers-Smith and 5 more

Abstract read
In one paragraph

Article in Journal of studies on alcohol and drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

April YoungDepartment of Epidemiology and Environmental Health, University of Kentucky College of Public Health, Lexington, Kentucky.
Ryli HockensmithDepartment of Epidemiology and Environmental Health, University of Kentucky College of Public Health, Lexington, Kentucky.
Preston T TolbertDepartment of Epidemiology and Environmental Health, University of Kentucky College of Public Health, Lexington, Kentucky.
Susan WestneatDepartment of Epidemiology and Environmental Health, University of Kentucky College of Public Health, Lexington, Kentucky.
Peter VickermanPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Jack StonePopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Hilary L SurrattCenter on Drug and Alcohol Research, Department of Behavioral Science, University of Kentucky College of Medicine, Lexington, Kentucky.
Kayo FujimotoDepartment of Health Promotion and Behavioral Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas.
Hannah K KnudsenCenter on Drug and Alcohol Research, Department of Behavioral Science, University of Kentucky College of Medicine, Lexington, Kentucky.
Rachel Vickers-SmithDepartment of Epidemiology and Environmental Health, University of Kentucky College of Public Health, Lexington, Kentucky.
Katherine L ThompsonDr. Bing Zhang Department of Statistics, University of Kentucky College of Arts & Sciences, Lexington, Kentucky.
Laura FanucchiCenter on Drug and Alcohol Research, Department of Behavioral Science, University of Kentucky College of Medicine, Lexington, Kentucky.
Julia KollitzDepartment of Epidemiology and Environmental Health, University of Kentucky College of Public Health, Lexington, Kentucky.
Jennifer R HavensCenter on Drug and Alcohol Research, Department of Behavioral Science, University of Kentucky College of Medicine, Lexington, Kentucky.
Melvin D LivingstonDepartment of Behavioral, Social, and Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, Georgia.

Funding

Examining the Impact of the Twin Epidemics of Methamphetamine and Opioid Use on Overdose, Risky Sex and Treatment Engagement among PWUD in Two Rural Appalachian CohortsR01DA033862 · NIDA · UNIVERSITY OF KENTUCKY · PI Jennifer R Havens · 2012 to 2026
$6.9M
Kentucky Outreach Service Kiosk (KyOSK): Reducing Overdose, Hepatitis C, and Other Drug-related Risks in Rural Appalachia through Health KiosksR01DA055872 · NIDA · UNIVERSITY OF KENTUCKY · PI April Marie Young · 2022 to 2026
$2.9M
Engaging People Who Use Drugs in Harm Reduction Service Delivery: An Intravention to Reduce Risk of HIV, HCV, Overdose, and Injection-related Infections in Rural AppalachiaR61DA061831 · NIDA · UNIVERSITY OF KENTUCKY · PI YOUNG, APRIL MARIE · 2024 to 2024
$1.5M
NIDA NIH HHS R01 DA033862NIDA NIH HHS R01 DA055872NIDA NIH HHS R61 DA061831
6 · The paper itself

Abstract

objectiveThis study aims to understand the characteristics of people who inject drugs approached by others for injection assistance.

methodPeer-referral and outreach were used to recruit rural adults who recently injected drugs in Appalachian Kentucky (n=435). Interviewer-administered questionnaires elicited data on participant characteristics and injection assistance. Descriptive statistics and generalized estimating equations clustered on peer-referral recruitment chain were used for analysis.

resultsNearly one-third (30.1%) reported others had come to them for injection assistance. People approached for assistance were slightly younger (prevalence ratio [PR]: 0.91, 95% confidence interval [CI]: 0.85-0.99) but otherwise, demographically similar to their counterparts. Those approached for assistance were more likely to have tested HCV antibody positive (PR: 1.65, 95%CI: 1.08-2.51), recently (past six months) engaged in distributive syringe sharing (PR: 1.33, 95%CI: 1.05-1.69), used buprenorphine "to get high" (PR: 1.32, 95%CI: 1.01-1.75), witnessed an overdose (PR: 1.71, 95%CI: 1.25-2.32), and used fentanyl test strips (PR: 1.54, 95%CI: 1.14-2.08). They were also more likely to have received safer injection education (PR: 1.43, 95%CI: 1.08-1.84) and less likely to believe that sterile syringes were easy to access (PR: 0.60, 95%CI: 0.40-0.88). Among those who visited the syringe services program (SSP), those approached for injection assistance provided more people with SSP-issued syringes (PR: 1.02, 95%CI: 1.01-1.03) than those not approached.

conclusionsInjection assistance is common in rural Appalachian Kentucky and those approached for assistance have unmet harm reduction needs. Interventions that improve syringe coverage and strengthen efforts to provide support to peers in this population are needed.

Indexed as

Appalachiaharm reductioninjection assistanceinjection drug use

Identifiers

PMID42212759
PMCPMC13314062

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.