ArticleJournal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie2026
Differences in orthodontic pain-related behavior between adolescent and adult rats.
Article in Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo analyze and compare the differences in orthodontic pain-related behavior between adolescent and adult rats.
methodsTwenty 6‑week-old male Sprague-Dawley rats were used to represent adolescent animals, and twenty 8‑month-old male Sprague-Dawley rats were used as adult animals. Ten animals of each group were randomly selected as the control group, and ten as the experimental group. In the experimental groups, each rat was subjected to an orthodontic force. Body weight, food intake weight, and face-grooming activity were recorded, and the open-field and light/dark box tests were conducted on days 1, 3, 7, and 10 after force loading.
resultsIn adolescent rats, body weight and food intake weight of the experimental group were lower than those of the control group at some time points. The frequency and duration of face grooming in the adolescent rats in the experimental group were greater than those in the control group. On day 1, the distance and frequency that the rats travelled in the center in the open-field test and the frequency that they entered the light box in the light/dark box test in the experimental group were less than in the control group. There was no obvious difference in the indices above between the control and experimental groups of the adult rats.
conclusionAdolescent and adult rats demonstrated different patterns of orthodontic pain-related behaviors. Compared with adult rats, adolescent rats exhibited more intense and earlier responses to orthodontic pain.
Indexed as
Identifiers
42213094What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.