Evidence map›Paper›PMID 42213575›Full record

ArticleJournal of animal science2026

Genetic and environmental factors affecting pregnancy loss in Nellore cattle: insights from a large-scale Brazilian field database.

Eriklis Nogueira, Roberto A de A Torres Junior, Luis Carlos L Ferreira, Dauydison A G Cordeiro, Felipe de Oliveira Pedro, Ivan Carvalho, Juan Cuevas de Alvarenga Martins, Fabiane Siqueira, Alexandre B Prata, Gilberto R Menezes and 4 more

Abstract read
In one paragraph

Article in Journal of animal science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Eriklis NogueiraEmpresa Brasileira de Pesquisa Agropecuária (Embrapa), Gado de Corte, Campo Grande, 79106-550, Brazil.ORCID 0000-0002-7931-455X
Roberto A de A Torres JuniorEmpresa Brasileira de Pesquisa Agropecuária (Embrapa), Gado de Corte, Campo Grande, 79106-550, Brazil.
Luis Carlos L FerreiraCia Pecuária Assessoria, Campo Grande, 79106-550, Brazil.
Dauydison A G CordeiroUniversidade Federal de Mato Grosso do Sul (CIVET-UFMS), Campo Grance, MS, 79070-900, Brazil.
Felipe de Oliveira PedroUniversidade Federal de Mato Grosso do Sul (CIVET-UFMS), Campo Grance, MS, 79070-900, Brazil.
Ivan CarvalhoEmpresa Brasileira de Pesquisa Agropecuária (Embrapa), Gado de Corte, Campo Grande, 79106-550, Brazil.
Juan Cuevas de Alvarenga MartinsUniversidade Federal de Mato Grosso do Sul (CIVET-UFMS), Campo Grance, MS, 79070-900, Brazil.
Fabiane SiqueiraEmpresa Brasileira de Pesquisa Agropecuária (Embrapa), Gado de Corte, Campo Grande, 79106-550, Brazil.
Alexandre B PrataUniversidade de São Paulo (ESALQ-USP), Piracicaba, SP, 13418-900, Brazil.
Gilberto R MenezesEmpresa Brasileira de Pesquisa Agropecuária (Embrapa), Gado de Corte, Campo Grande, 79106-550, Brazil.
Pamela Itajara OttoUniversidade Federal de Santa Maria, Santa Maria, 97105-900, Brazil.
Peter SutovskyDivision of Animal Sciences, and Department of Obstetrics, Gynecology & Women's Health, University of Missouri, Columbia, MO, 65211, United States.ORCID 0000-0002-9231-2823
Joao G N MoraesDepartment of Animal and Food Sciences, Oklahoma State University, Stillwater, OK, 74078, United States.
Sabrina T AmorimDepartment of Animal and Food Sciences, Oklahoma State University, Stillwater, OK, 74078, United States.ORCID 0000-0003-4130-2040

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy loss (PL) is a major constraint on reproductive efficiency in beef cattle, yet its genetic basis remains poorly understood. This study aimed to estimate genetic parameters for PL and to quantify sire-related variation in Nellore cattle managed under Fixed-Time Artificial Insemination (FTAI). Records from 305,325 FTAI services involving 667 Nellore sires, collected across 271 farms in Brazil between 2015 and 2022, were analyzed. PL was modeled as a binary trait using a Bayesian threshold sire model, assuming an underlying continuous liability. Fixed effects included contemporary group, dam category, body condition score, and cow age at pregnancy diagnosis, and sire effects were modeled as random. Variance components and sire effects were estimated via Markov Chain Monte Carlo sampling implemented in the BLUPF90+ software suite, and the accuracy of sire evaluations was computed following the Beef Improvement Federation (BIF) guidelines based on prediction error variance. PL exhibited low heritability on the liability scale (h2 = 0.031; 95% HPD: 0.019-0.042), indicating that most of the variation is driven by environmental factors, and meaningful variation among sires was detected. PL rates averaged 6.64% in multiparous cows, 8.28% in primiparous cows, and up to 12.35% in precocious heifers. Approximately 15% of sires achieved BIF accuracy values of 0.24 or greater, and contrasts between the top and bottom deciles of sires were associated with a 31% increase in PL among precocious heifers. PL was also strongly influenced by age and dam category, with higher rates observed in younger females, particularly precocious heifers, and declining with increasing age and parity. Overall, these results demonstrate that, although PL has low heritability, exploitable genetic variation among sires exists when supported by large, well-structured FTAI datasets. Integrating PL indicators into multi-trait selection indices with targeted nutritional and reproductive management offers a practical strategy to improve reproductive efficiency in beef cattle production systems.

Indexed as

Abortion, VeterinaryCattle DiseasesAnimalsBrazilCattleEnvironmentFemaleInsemination, ArtificialPregnancyabortionbeef cattlebiotechnologyextensivetropical climate

Identifiers

PMID42213575
PMCPMC13294443

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.