Evidence map›Paper›PMID 42214788›Full record

ArticleJournal of sport and health science2026

Functional characteristics in supraspinal networks and sensorimotor function following individualized dose-controlled HD-tDCS during foot core exercise in chronic ankle instability.

Songlin Xiao, Chuyi Zhang, Bin Shen, Zhen Xu, Junhong Zhou, Weijie Fu

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In one paragraph

Article in Journal of sport and health science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Songlin XiaoSchool of Sports Medicine and Health, Chengdu Sport University, Chengdu 641418, China; Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai 200438, China.
Chuyi ZhangKey Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai 200438, China.
Bin ShenKey Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai 200438, China.
Zhen XuKey Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai 200438, China.
Junhong ZhouThe Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA 02131, USA; Department of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02131, USA. Electronic address: junhongzhou@hsl.harvard.edu.
Weijie FuSchool of Intelligent Sports Engineering, Shanghai University of Sport, Shanghai 200438, China. Electronic address: fuweijie@sus.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to investigate the effects of individualized dose-controlled high-definition transcranial direct current stimulation (HD-tDCS) in combination with foot core exercise (FCE) on functional supraspinal network characteristics and sensorimotor function in individuals with chronic ankle instability (CAI).

methodsIn this double-blind, randomized controlled trial, 34 participants were allocated into 2 groups: individualized dose-controlled HD-tDCS combined with FCE and sham stimulation combined with FCE (control group). Participants received 20 min of stimulation concurrent with FCE, 3 times per week over a 4-week period. Assessments included task-related functional magnetic resonance imaging and ankle force sense, conducted at baseline and post-intervention.

resultsCompared with baseline and the control group, the individualized dose-controlled HD-tDCS combined with FCE reduced task-related cortical activation in the bilateral inferior parietal lobule and the right supplementary motor area (rSMA) and increased functional connectivity (FC) between the left inferior parietal lobule and the right putamen. Additionally, improved dorsiflexion, inversion, and eversion force senses were observed. Besides, changes in force sense were negatively correlated with changes in signal intensities in the right inferior parietal lobule and rSMA, and marginally significantly associated with changes in FC between the left inferior parietal lobule and right putamen.

conclusionA 4-week intervention of individualized dose-controlled HD-tDCS combined with FCE effectively reduced cortical activation during ankle motor tasks, strengthened FC within relevant supraspinal networks, and enhanced sensorimotor function in individuals with CAI.

Indexed as

Cortical activationFoot core exerciseForce senseIndividualized dose-controlled high-definition transcranial direct current stimulationSensorimotor function

Identifiers

PMID42214788
PMCPMC13449825

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.