ArticleJournal of occupational medicine and toxicology (London, England)2026
Seven-year surveillance of latent tuberculosis infection using interferon-gamma release assay among health workers at a large tertiary hospital in Thailand.
Article in Journal of occupational medicine and toxicology (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundDespite ongoing TB control efforts, health workers (HWs) in Thailand remain at risk for latent tuberculosis infection (LTBI), yet the burden of LTBI in Thai HWs is insufficiently characterized. This study aimed to determine LTBI proportions across preplacement, post-exposure, and annual screening approaches, and to identify factors associated with LTBI among HWs.
methodsThis retrospective analysis (2016-2022) utilized secondary data from an LTBI surveillance program at a large Thai tertiary hospital. HWs underwent LTBI screening with interferon-gamma release assays (IGRAs) through three surveillance approaches: preplacement, post-exposure, and annual screening in high-risk units (2021-2022). LTBI was defined as IGRA-positive in the absence of active TB. Demographic and exposure characteristics were recorded; associations were analyzed using chi-square and Mann-Whitney U tests. An exploratory restricted analysis using multivariable logistic regression was also performed to assess between-cohort patterns.
resultsBetween 2016 and 2020, LTBI was detected in 198 of 1,823 HWs (10.9%; 95% CI: 9.5-12.4). Preplacement screening identified LTBI in 96 of 1,230 HWs (7.8%; 95% CI: 6.5-9.5), while post-exposure surveillance detected LTBI in 102 of 706 HWs (14.4%; 95% CI: 12.1-17.2). Annual surveillance (2021-2022) yielded 47 cases among 626 HWs (7.5%; 95% CI: 5.7-9.8). Among HWs diagnosed with LTBI in the preplacement and post-exposure cohorts, 40.9% of LTBI cases initiated TB preventive treatment. In post-exposure surveillance, older age and higher exposure-priority categories were associated with LTBI, although estimates for priority categories were imprecise because of sparse data.
conclusionsLTBI remains an important occupational health concern among HWs, with the highest detection proportion observed during post-exposure surveillance. These findings highlight the ongoing need for targeted, risk-based monitoring and efforts to enhance TB preventive treatment uptake in healthcare settings.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.