Diet, exercise & lifestyle × glycemic control

SynthesisMedicine2026

Triple oral therapy combining metformin, SGLT-2 and DPP-4 inhibitors versus dual therapy in type 2 diabetes mellitus: A systematic review and meta-analysis.

Abdul Fatah Malik et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 2,606 people · 2026

Range includes no effect

No clear effect on glycemic control

−0.30−0.62 to +0.01

As reported

difference −0.30, 95% CI −0.62 to 0.01

One number in the abstract

the abstract, start to end

fasting plasma glucose, with an SMD of -0.30 (95% CI: -0.62 to 0.01;

← favours treatmentfavours comparator →
could be chance
Glycemic control
−0.30−0.62 to 0.01
Diet, exercise & lifestyleGlycemic control
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Full record →Abstract, authors, funding and every citing paper · PMID 42216339