ArticleMagnetic resonance in medicine2026
Multiple-TE Based Blood-Brain-Barrier Water Exchange Time Measurement Using a TE-Resolved 3D TSE Stack-Of-Spirals Readout.
Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Multiple-TE Based Blood-Brain-Barrier Water Exchange Time Measurement Using a TE-Resolved 3D TSE Stack-Of-Spirals Readout.Magnetic resonance in medicine · 2026Article
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Authors and funding
12 authors.
Funding
Abstract
purposeTo develop a slice-wise blurring-free and densely sampled TE-resolved multiple-TE (mTE) ASL sequence (TASL) for measuring blood-brain barrier (BBB) water exchange time.
methodsA 3D TSE spiral-readout pCASL sequence was modified to enable TE-resolved acquisition. Signals at mTEs from a single kz partition were acquired within a single shot, and the acquisition was repeated until all required kz partitions were covered. In vivo experiments were conducted on healthy volunteers using both a conventional pCASL sequence and the proposed TASL sequence. Signal intensity modulation, perfusion SNR, and quantitative parameters including cerebral blood flow (CBF), arterial transit time (ATT), intravoxel transit time (ITT), and water exchange time (T
resultsCompared with the conventional mTE acquisition, TASL eliminates T
conclusionTASL eliminates signal intensity modulation and blurring artifacts while providing densely sampled TE for parametric fitting. It may be a valuable tool for accurate and reliable quantification of cerebral perfusion and BBB permeability.
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