ArticleWorld journal of surgery2026
Postoperative Function and Quality of Life of Patients With Low Rectal Cancer: A Multidimensional Comparison Between Low Anterior Resection and Abdominoperineal Resection.
Article in World journal of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe choice between low anterior resection (LAR) and abdominoperineal resection (APR) for low rectal cancer involves complex trade-offs between sphincter preservation and functional outcomes.
objectiveThis study aimed to compare overall quality of life (QoL), colorectal-specific symptoms, and functional outcomes between LAR and APR at ≥ 12 months post-surgery and to identify influencing factors.
methodsThis single-center retrospective cohort study included patients who underwent LAR or APR for low rectal cancer (≤ 5 cm from the anal verge) between January 2019 and December 2023. Patients completed validated questionnaires 12-60 months post-surgery. Inverse probability of treatment weighting was employed to adjust for baseline imbalances.
resultsOut of 168 eligible patients, 142 (84.5%) completed assessments (LAR n = 78, APR n = 64). After adjustment, the mean global health status was 68.3 ± 18.5 for LAR versus 71.2 ± 16.8 for APR (adjusted mean difference -2.9, p = 0.302). Major low-anterior resection syndrome affected 44.9% of LAR patients, whereas 31.3% of APR patients reported poor stoma-related QoL. Sexual dysfunction was prevalent in both groups. Neoadjuvant chemoradiotherapy and tumor distance ≤ 3 cm predicted major LARS. LARS severity did not perfectly align with QoL impairment; 20.0% of patients with minor LARS reported poor QoL, whereas 22.9% with major LARS maintained good QoL.
conclusionsNo clinically meaningful difference in overall QoL was observed between LAR and APR at long-term follow-up. However, procedure-specific challenges exist; major LARS affects nearly half of LAR patients, and one-third of APR patients report poor stoma-related QoL. These findings support individualized surgical decision-making based on patient priorities and risk factors.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.