Evidence map›Paper›PMID 42217118›Full record

ArticleGeneral thoracic and cardiovascular surgery2026

Risk factors associated with saphenous vein graft in-stent restenosis.

Alireza Amirzadegan, Reza Ebadi, Hamid Khederlou, Pouya Karami Dehkordi, Zahra Karimi

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Article in General thoracic and cardiovascular surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Alireza AmirzadeganTehran Heart Center, Cardiovascular Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Reza EbadiInterventional Cardiologist, Ardabil University of Medical Sciences, Ardabil, Iran.
Hamid KhederlouDepartment of Cardiology, Zanjan University of Medical Sciences, Zanjan, Iran. dr.khederlou@gmail.com.ORCID http://orcid.org/0000-0001-8606-2381
Pouya Karami DehkordiStudent Research Committee, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Zahra KarimiTehran Heart Center, Cardiovascular Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Funding

Tehran University of Medical Sciences and Health Services Tehran University of Medical Sciences and Health Services
6 · The paper itself

Abstract

objectiveThis study examined the risk factors of in-stent restenosis (ISR) group after saphenous vein grafts (SVGs) percutaneous coronary intervention.

methodsFrom March 2007 to February 2021, we collected 385 cases of SVGs percutaneous coronary intervention at the Tehran heart center. Patients experiencing ischemic symptoms were examined during follow-ups by cardiologists, who recommended a second coronary artery angiography. On the basis of coronary artery angiography, the cases were classified as ISR group (n = 284) or non-ISR group (n = 101). The medical history, biochemical indicators, coronary artery lesion features, and stent characteristics were retrospectively evaluated. Using univariate and multivariable Cox regression, risk factors for ISR group have been discovered.

resultsSVG ISR group was verified in 284 of the total number of patients (73.8%). The median length of follow-up was 8.6 years (95% CI = 7.1-10.0 years). Lower body mass index (HR = 0.95, 95% CI = 0.92-0.98, p = 0.006), lower left ventricular ejection fraction (HR = 0.94, 95% CI = 0.91-0.99, p = 0.001), and longer stent length (HR = 1.03, 95% CI = 1.01-1.05, p = 0.002), remained independently associated with ISR group after multivariable analysis.

conclusionLower body mass index, lower left ventricular ejection fraction, and longer stent length are independent predictors of ISR group after SVGs percutaneous coronary intervention.

Indexed as

Coronary artery bypass graft surgeryIn-stent restenosisPercutaneous coronary interventionSaphenous vein graft

Identifiers

PMID42217118

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.